Transplantation of hepatocytes from genetically engineered pigs into baboons

Background Some patients with acute or acute‐on‐chronic hepatic failure die before a suitable human liver allograft becomes available. Encouraging results have been achieved in such patients by the transplantation of human hepatocyte progenitor cells from fetal liver tissue. The aim of the study was...

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Veröffentlicht in:	Xenotransplantation (Københaven) 2017-03, Vol.24 (2), p.np-n/a
Hauptverfasser:	Iwase, Hayato, Liu, Hong, Schmelzer, Eva, Ezzelarab, Mohamed, Wijkstrom, Martin, Hara, Hidetaka, Lee, Whayoung, Singh, Jagjit, Long, Cassandra, Lagasse, Eric, Gerlach, Jörg C., Cooper, David K. C., Gridelli, Bruno
Format:	Artikel
Sprache:	eng
Schlagworte:	Albumen Albumin Allografts Animals Animals, Genetically Modified Antibodies Antibodies - immunology Antibody Formation - genetics Antibody Formation - immunology Antigens Antigens - immunology baboon Clinical trials Enzyme-linked immunosorbent assay Fetuses Flow cytometry Gene expression Genetic engineering Globulins Graft Survival - drug effects Graft Survival - immunology Heart hepatocytes Hepatocytes - immunology Hepatocytes - transplantation Immune response Immunogenicity Immunoglobulin G Immunoglobulin M Immunosuppression Immunosuppression - methods Immunosuppressive Agents - pharmacology Liver Lymph nodes Mixed leukocyte reaction Papio hamadryas - immunology pig Polymerase chain reaction Spleen Stem cells Swine Tacrolimus Transplantation Transplantation, Heterologous - methods xenotransplantation
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