A highly regular fucosylated chondroitin sulfate from the sea cucumber Massinium magnum: Structure and effects on coagulation

•The structure of the natural fucosylated chondroitin sulfate (FCS) was determined.•The sea cucumber Massinium magnum was used as a source of FCS.•The backbone of the polysaccharide consists mainly of chondroitin sulfate E units.•The only one type of Fuc3S4S branches attached to O-3 of GlcA was foun...

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Veröffentlicht in:	Carbohydrate polymers 2017-07, Vol.167, p.20-26
Hauptverfasser:	Ustyuzhanina, Nadezhda E., Bilan, Maria I., Dmitrenok, Andrey S., Borodina, Elizaveta Yu, Stonik, Valentin A., Nifantiev, Nikolay E., Usov, Anatolii I.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Anticoagulant Blood Coagulation - drug effects Chondroitin Sulfates - chemistry Fucose Fucosylated chondroitin sulfate Humans Massinium magnum Platelet Aggregation - drug effects Sea cucumber Sea Cucumbers - chemistry Structure Thrombin Time
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