Chronic nicotine attenuates behavioral and synaptic plasticity impairments in a streptozotocin model of Alzheimer’s disease
Highlights • STZ-icv induced dysfunction in CA1-mPFC plasticity and recognition memory. • Nicotine was effective to prevent prefrontal LTP and memory deficits induced by. • STZ-icv. • Modulation of nicotinic receptor might be an alternative approach for AD treatment.
Gespeichert in:
| Veröffentlicht in: | Neuroscience 2017-06, Vol.353, p.87-97 |
|---|---|
| Hauptverfasser: | , , , , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 97 |
|---|---|
| container_issue | |
| container_start_page | 87 |
| container_title | Neuroscience |
| container_volume | 353 |
| creator | IM, Esteves C, Lopes-Aguiar MT, Rossignoli RN, Ruggiero ACS, Broggini LS, Bueno-Junior L, Kandratavicius MR, Monteiro RN, Romcy-Pereira JP, Leite |
| description | Highlights • STZ-icv induced dysfunction in CA1-mPFC plasticity and recognition memory. • Nicotine was effective to prevent prefrontal LTP and memory deficits induced by. • STZ-icv. • Modulation of nicotinic receptor might be an alternative approach for AD treatment. |
| doi_str_mv | 10.1016/j.neuroscience.2017.04.011 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_1891455647</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>S0306452217302580</els_id><sourcerecordid>1891455647</sourcerecordid><originalsourceid>FETCH-LOGICAL-c487t-75e3eb30d9b2f8b79c59e7baf3c15a52b05340bd35f3a31bccd60bcbf8cd90523</originalsourceid><addsrcrecordid>eNqNktuKFDEQhoO4uOPqK0jwyptpk07SBy-EZdYTLHihXoccqpmM3UmbpBdmQfA19vV8EjPMuCxeWVAUhL_-or4UQi8pqSihzetd5WGJIRkH3kBVE9pWhFeE0kdoRbuWrVvB-WO0Iow0ay7q-hw9TWlHSgjOnqDzuuOMNbxfoZ-bbQzeGVwyZOcBq5zBLypDwhq26saFqEasvMVp79Wci3YeVSrV5T1206xcnMDnhJ3HCqccYc7hNuRgysMULIw4DPhyvN2CmyD-_nWXsHUJVIJn6GxQY4Lnp3qBvr1_93XzcX39-cOnzeX12vCuzWUdYKAZsb2uh063vRE9tFoNzFChRK2JYJxoy8TAFKPaGNsQbfTQGdsTUbML9OroO8fwY4GU5eSSgXFUHsKSJO16yoVoeFukb45SUwinCIOco5tU3EtK5AG_3MmH-OUBvyRcFvyl-cVpzqInsPetf3kXwdVRAGXbGwdRnmysi2CytMH935y3_9iY0ZUfVON32EPahSX6wlNSmWpJ5JfDIRzugLaM1KIj7A9qprdy</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1891455647</pqid></control><display><type>article</type><title>Chronic nicotine attenuates behavioral and synaptic plasticity impairments in a streptozotocin model of Alzheimer’s disease</title><source>MEDLINE</source><source>Elsevier ScienceDirect Journals</source><creator>IM, Esteves ; C, Lopes-Aguiar ; MT, Rossignoli ; RN, Ruggiero ; ACS, Broggini ; LS, Bueno-Junior ; L, Kandratavicius ; MR, Monteiro ; RN, Romcy-Pereira ; JP, Leite</creator><creatorcontrib>IM, Esteves ; C, Lopes-Aguiar ; MT, Rossignoli ; RN, Ruggiero ; ACS, Broggini ; LS, Bueno-Junior ; L, Kandratavicius ; MR, Monteiro ; RN, Romcy-Pereira ; JP, Leite</creatorcontrib><description>Highlights • STZ-icv induced dysfunction in CA1-mPFC plasticity and recognition memory. • Nicotine was effective to prevent prefrontal LTP and memory deficits induced by. • STZ-icv. • Modulation of nicotinic receptor might be an alternative approach for AD treatment.</description><identifier>ISSN: 0306-4522</identifier><identifier>EISSN: 1873-7544</identifier><identifier>DOI: 10.1016/j.neuroscience.2017.04.011</identifier><identifier>PMID: 28433649</identifier><language>eng</language><publisher>United States: Elsevier Ltd</publisher><subject>Alzheimer Disease - chemically induced ; Alzheimer Disease - physiopathology ; Alzheimer Disease - psychology ; Alzheimer’s disease ; Animals ; CA1 Region, Hippocampal - drug effects ; CA1 Region, Hippocampal - physiology ; Cell Count ; Disease Models, Animal ; Locomotion - drug effects ; long-term potentiation ; Long-Term Potentiation - drug effects ; Male ; Neurology ; Neurons - drug effects ; nicotine ; Nicotine - administration & dosage ; Prefrontal Cortex - drug effects ; Prefrontal Cortex - physiology ; Rats, Wistar ; Recognition (Psychology) - drug effects ; Recognition (Psychology) - physiology ; recognition memory ; Streptozocin ; streptozotocin ; synaptic plasticity ; Synaptic Potentials - drug effects</subject><ispartof>Neuroscience, 2017-06, Vol.353, p.87-97</ispartof><rights>IBRO</rights><rights>2017 IBRO</rights><rights>Copyright © 2017 IBRO. Published by Elsevier Ltd. All rights reserved.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c487t-75e3eb30d9b2f8b79c59e7baf3c15a52b05340bd35f3a31bccd60bcbf8cd90523</citedby><cites>FETCH-LOGICAL-c487t-75e3eb30d9b2f8b79c59e7baf3c15a52b05340bd35f3a31bccd60bcbf8cd90523</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/j.neuroscience.2017.04.011$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,777,781,3537,27905,27906,45976</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/28433649$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>IM, Esteves</creatorcontrib><creatorcontrib>C, Lopes-Aguiar</creatorcontrib><creatorcontrib>MT, Rossignoli</creatorcontrib><creatorcontrib>RN, Ruggiero</creatorcontrib><creatorcontrib>ACS, Broggini</creatorcontrib><creatorcontrib>LS, Bueno-Junior</creatorcontrib><creatorcontrib>L, Kandratavicius</creatorcontrib><creatorcontrib>MR, Monteiro</creatorcontrib><creatorcontrib>RN, Romcy-Pereira</creatorcontrib><creatorcontrib>JP, Leite</creatorcontrib><title>Chronic nicotine attenuates behavioral and synaptic plasticity impairments in a streptozotocin model of Alzheimer’s disease</title><title>Neuroscience</title><addtitle>Neuroscience</addtitle><description>Highlights • STZ-icv induced dysfunction in CA1-mPFC plasticity and recognition memory. • Nicotine was effective to prevent prefrontal LTP and memory deficits induced by. • STZ-icv. • Modulation of nicotinic receptor might be an alternative approach for AD treatment.</description><subject>Alzheimer Disease - chemically induced</subject><subject>Alzheimer Disease - physiopathology</subject><subject>Alzheimer Disease - psychology</subject><subject>Alzheimer’s disease</subject><subject>Animals</subject><subject>CA1 Region, Hippocampal - drug effects</subject><subject>CA1 Region, Hippocampal - physiology</subject><subject>Cell Count</subject><subject>Disease Models, Animal</subject><subject>Locomotion - drug effects</subject><subject>long-term potentiation</subject><subject>Long-Term Potentiation - drug effects</subject><subject>Male</subject><subject>Neurology</subject><subject>Neurons - drug effects</subject><subject>nicotine</subject><subject>Nicotine - administration & dosage</subject><subject>Prefrontal Cortex - drug effects</subject><subject>Prefrontal Cortex - physiology</subject><subject>Rats, Wistar</subject><subject>Recognition (Psychology) - drug effects</subject><subject>Recognition (Psychology) - physiology</subject><subject>recognition memory</subject><subject>Streptozocin</subject><subject>streptozotocin</subject><subject>synaptic plasticity</subject><subject>Synaptic Potentials - drug effects</subject><issn>0306-4522</issn><issn>1873-7544</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2017</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqNktuKFDEQhoO4uOPqK0jwyptpk07SBy-EZdYTLHihXoccqpmM3UmbpBdmQfA19vV8EjPMuCxeWVAUhL_-or4UQi8pqSihzetd5WGJIRkH3kBVE9pWhFeE0kdoRbuWrVvB-WO0Iow0ay7q-hw9TWlHSgjOnqDzuuOMNbxfoZ-bbQzeGVwyZOcBq5zBLypDwhq26saFqEasvMVp79Wci3YeVSrV5T1206xcnMDnhJ3HCqccYc7hNuRgysMULIw4DPhyvN2CmyD-_nWXsHUJVIJn6GxQY4Lnp3qBvr1_93XzcX39-cOnzeX12vCuzWUdYKAZsb2uh063vRE9tFoNzFChRK2JYJxoy8TAFKPaGNsQbfTQGdsTUbML9OroO8fwY4GU5eSSgXFUHsKSJO16yoVoeFukb45SUwinCIOco5tU3EtK5AG_3MmH-OUBvyRcFvyl-cVpzqInsPetf3kXwdVRAGXbGwdRnmysi2CytMH935y3_9iY0ZUfVON32EPahSX6wlNSmWpJ5JfDIRzugLaM1KIj7A9qprdy</recordid><startdate>20170614</startdate><enddate>20170614</enddate><creator>IM, Esteves</creator><creator>C, Lopes-Aguiar</creator><creator>MT, Rossignoli</creator><creator>RN, Ruggiero</creator><creator>ACS, Broggini</creator><creator>LS, Bueno-Junior</creator><creator>L, Kandratavicius</creator><creator>MR, Monteiro</creator><creator>RN, Romcy-Pereira</creator><creator>JP, Leite</creator><general>Elsevier Ltd</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20170614</creationdate><title>Chronic nicotine attenuates behavioral and synaptic plasticity impairments in a streptozotocin model of Alzheimer’s disease</title><author>IM, Esteves ; C, Lopes-Aguiar ; MT, Rossignoli ; RN, Ruggiero ; ACS, Broggini ; LS, Bueno-Junior ; L, Kandratavicius ; MR, Monteiro ; RN, Romcy-Pereira ; JP, Leite</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c487t-75e3eb30d9b2f8b79c59e7baf3c15a52b05340bd35f3a31bccd60bcbf8cd90523</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2017</creationdate><topic>Alzheimer Disease - chemically induced</topic><topic>Alzheimer Disease - physiopathology</topic><topic>Alzheimer Disease - psychology</topic><topic>Alzheimer’s disease</topic><topic>Animals</topic><topic>CA1 Region, Hippocampal - drug effects</topic><topic>CA1 Region, Hippocampal - physiology</topic><topic>Cell Count</topic><topic>Disease Models, Animal</topic><topic>Locomotion - drug effects</topic><topic>long-term potentiation</topic><topic>Long-Term Potentiation - drug effects</topic><topic>Male</topic><topic>Neurology</topic><topic>Neurons - drug effects</topic><topic>nicotine</topic><topic>Nicotine - administration & dosage</topic><topic>Prefrontal Cortex - drug effects</topic><topic>Prefrontal Cortex - physiology</topic><topic>Rats, Wistar</topic><topic>Recognition (Psychology) - drug effects</topic><topic>Recognition (Psychology) - physiology</topic><topic>recognition memory</topic><topic>Streptozocin</topic><topic>streptozotocin</topic><topic>synaptic plasticity</topic><topic>Synaptic Potentials - drug effects</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>IM, Esteves</creatorcontrib><creatorcontrib>C, Lopes-Aguiar</creatorcontrib><creatorcontrib>MT, Rossignoli</creatorcontrib><creatorcontrib>RN, Ruggiero</creatorcontrib><creatorcontrib>ACS, Broggini</creatorcontrib><creatorcontrib>LS, Bueno-Junior</creatorcontrib><creatorcontrib>L, Kandratavicius</creatorcontrib><creatorcontrib>MR, Monteiro</creatorcontrib><creatorcontrib>RN, Romcy-Pereira</creatorcontrib><creatorcontrib>JP, Leite</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Neuroscience</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>IM, Esteves</au><au>C, Lopes-Aguiar</au><au>MT, Rossignoli</au><au>RN, Ruggiero</au><au>ACS, Broggini</au><au>LS, Bueno-Junior</au><au>L, Kandratavicius</au><au>MR, Monteiro</au><au>RN, Romcy-Pereira</au><au>JP, Leite</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Chronic nicotine attenuates behavioral and synaptic plasticity impairments in a streptozotocin model of Alzheimer’s disease</atitle><jtitle>Neuroscience</jtitle><addtitle>Neuroscience</addtitle><date>2017-06-14</date><risdate>2017</risdate><volume>353</volume><spage>87</spage><epage>97</epage><pages>87-97</pages><issn>0306-4522</issn><eissn>1873-7544</eissn><abstract>Highlights • STZ-icv induced dysfunction in CA1-mPFC plasticity and recognition memory. • Nicotine was effective to prevent prefrontal LTP and memory deficits induced by. • STZ-icv. • Modulation of nicotinic receptor might be an alternative approach for AD treatment.</abstract><cop>United States</cop><pub>Elsevier Ltd</pub><pmid>28433649</pmid><doi>10.1016/j.neuroscience.2017.04.011</doi><tpages>11</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0306-4522 |
| ispartof | Neuroscience, 2017-06, Vol.353, p.87-97 |
| issn | 0306-4522 1873-7544 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_1891455647 |
| source | MEDLINE; Elsevier ScienceDirect Journals |
| subjects | Alzheimer Disease - chemically induced Alzheimer Disease - physiopathology Alzheimer Disease - psychology Alzheimer’s disease Animals CA1 Region, Hippocampal - drug effects CA1 Region, Hippocampal - physiology Cell Count Disease Models, Animal Locomotion - drug effects long-term potentiation Long-Term Potentiation - drug effects Male Neurology Neurons - drug effects nicotine Nicotine - administration & dosage Prefrontal Cortex - drug effects Prefrontal Cortex - physiology Rats, Wistar Recognition (Psychology) - drug effects Recognition (Psychology) - physiology recognition memory Streptozocin streptozotocin synaptic plasticity Synaptic Potentials - drug effects |
| title | Chronic nicotine attenuates behavioral and synaptic plasticity impairments in a streptozotocin model of Alzheimer’s disease |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-19T20%3A50%3A55IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Chronic%20nicotine%20attenuates%20behavioral%20and%20synaptic%20plasticity%20impairments%20in%20a%20streptozotocin%20model%20of%20Alzheimer%E2%80%99s%20disease&rft.jtitle=Neuroscience&rft.au=IM,%20Esteves&rft.date=2017-06-14&rft.volume=353&rft.spage=87&rft.epage=97&rft.pages=87-97&rft.issn=0306-4522&rft.eissn=1873-7544&rft_id=info:doi/10.1016/j.neuroscience.2017.04.011&rft_dat=%3Cproquest_cross%3E1891455647%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1891455647&rft_id=info:pmid/28433649&rft_els_id=S0306452217302580&rfr_iscdi=true |