Radiation therapy for recurrent cardiac undifferentiated pleomorphic sarcoma after three operations
We report the case of a 57-year-old female suffering from recurrent malignant undifferentiated pleomorphic sarcoma of the left atrium. Metastasis to the posterior mediastinum was detected upon first presentation. Incomplete resections were carried out twice before mitral valve replacement was finall...
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Veröffentlicht in: | General thoracic and cardiovascular surgery 2018-03, Vol.66 (3), p.168-171 |
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creator | Hirooka, Kazunobu Oonuki, Masahiro Manabe, Susumu Hiraoka, Daisuke Yasukawa, Takashi Suzuki, Keiko |
description | We report the case of a 57-year-old female suffering from recurrent malignant undifferentiated pleomorphic sarcoma of the left atrium. Metastasis to the posterior mediastinum was detected upon first presentation. Incomplete resections were carried out twice before mitral valve replacement was finally performed. The tumor recurred 16 months later and was treated with radiation therapy, which has proved to be effective in bringing about tumor regression for 2 years, to date. The patient has survived for 7 years since the first surgery. |
doi_str_mv | 10.1007/s11748-017-0771-3 |
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Metastasis to the posterior mediastinum was detected upon first presentation. Incomplete resections were carried out twice before mitral valve replacement was finally performed. The tumor recurred 16 months later and was treated with radiation therapy, which has proved to be effective in bringing about tumor regression for 2 years, to date. The patient has survived for 7 years since the first surgery.</description><identifier>ISSN: 1863-6705</identifier><identifier>EISSN: 1863-6713</identifier><identifier>DOI: 10.1007/s11748-017-0771-3</identifier><identifier>PMID: 28434140</identifier><language>eng</language><publisher>Tokyo: Springer Japan</publisher><subject>Cardiac Surgery ; Cardiac Surgical Procedures ; Cardiology ; Case Report ; Chemotherapy ; Dose Fractionation ; Dyspnea ; Female ; Heart Atria - pathology ; Heart Neoplasms - diagnostic imaging ; Heart Neoplasms - radiotherapy ; Heart Neoplasms - surgery ; Histiocytoma, Malignant Fibrous - diagnostic imaging ; Histiocytoma, Malignant Fibrous - radiotherapy ; Histiocytoma, Malignant Fibrous - surgery ; Humans ; Medical prognosis ; Medicine ; Medicine & Public Health ; Metastasis ; Middle Aged ; Neoplasm Recurrence, Local - diagnostic imaging ; Neoplasm Recurrence, Local - radiotherapy ; Ostomy ; Prostheses ; Radiation therapy ; Radiotherapy Dosage ; Sarcoma ; Surgery ; Surgical Oncology ; Thoracic Surgery ; Tomography, X-Ray Computed</subject><ispartof>General thoracic and cardiovascular surgery, 2018-03, Vol.66 (3), p.168-171</ispartof><rights>The Japanese Association for Thoracic Surgery 2017</rights><rights>The Japanese Association for Thoracic Surgery 2017.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c396t-e42878e8105e456abbe117611c1bb1db8791f43db9e3fbcfbfae41b74c06cb333</citedby><cites>FETCH-LOGICAL-c396t-e42878e8105e456abbe117611c1bb1db8791f43db9e3fbcfbfae41b74c06cb333</cites><orcidid>0000-0001-7178-2562</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s11748-017-0771-3$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://www.proquest.com/docview/2918739279?pq-origsite=primo$$EHTML$$P50$$Gproquest$$H</linktohtml><link.rule.ids>314,777,781,21369,21370,27905,27906,33511,33512,33725,33726,41469,42538,43640,43786,51300,64364,64366,64368,72218</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/28434140$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Hirooka, Kazunobu</creatorcontrib><creatorcontrib>Oonuki, Masahiro</creatorcontrib><creatorcontrib>Manabe, Susumu</creatorcontrib><creatorcontrib>Hiraoka, Daisuke</creatorcontrib><creatorcontrib>Yasukawa, Takashi</creatorcontrib><creatorcontrib>Suzuki, Keiko</creatorcontrib><title>Radiation therapy for recurrent cardiac undifferentiated pleomorphic sarcoma after three operations</title><title>General thoracic and cardiovascular surgery</title><addtitle>Gen Thorac Cardiovasc Surg</addtitle><addtitle>Gen Thorac Cardiovasc Surg</addtitle><description>We report the case of a 57-year-old female suffering from recurrent malignant undifferentiated pleomorphic sarcoma of the left atrium. Metastasis to the posterior mediastinum was detected upon first presentation. Incomplete resections were carried out twice before mitral valve replacement was finally performed. The tumor recurred 16 months later and was treated with radiation therapy, which has proved to be effective in bringing about tumor regression for 2 years, to date. The patient has survived for 7 years since the first surgery.</description><subject>Cardiac Surgery</subject><subject>Cardiac Surgical Procedures</subject><subject>Cardiology</subject><subject>Case Report</subject><subject>Chemotherapy</subject><subject>Dose Fractionation</subject><subject>Dyspnea</subject><subject>Female</subject><subject>Heart Atria - pathology</subject><subject>Heart Neoplasms - diagnostic imaging</subject><subject>Heart Neoplasms - radiotherapy</subject><subject>Heart Neoplasms - surgery</subject><subject>Histiocytoma, Malignant Fibrous - diagnostic imaging</subject><subject>Histiocytoma, Malignant Fibrous - radiotherapy</subject><subject>Histiocytoma, Malignant Fibrous - surgery</subject><subject>Humans</subject><subject>Medical prognosis</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Metastasis</subject><subject>Middle Aged</subject><subject>Neoplasm Recurrence, Local - diagnostic imaging</subject><subject>Neoplasm Recurrence, Local - radiotherapy</subject><subject>Ostomy</subject><subject>Prostheses</subject><subject>Radiation therapy</subject><subject>Radiotherapy Dosage</subject><subject>Sarcoma</subject><subject>Surgery</subject><subject>Surgical Oncology</subject><subject>Thoracic Surgery</subject><subject>Tomography, X-Ray Computed</subject><issn>1863-6705</issn><issn>1863-6713</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2018</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><recordid>eNp1kctq3jAQRkVpaS7tA3RTBN1041RjyZa8DKFtAoFASNZCkkeJw2_LGdmLvH1k_lyg0JWEdHQ0Mx9j30CcgBD6VwbQylQCdCW0hkp-YIdgWlm1GuTHt71oDthRzg9CNK2B5jM7qI2SCpQ4ZOHa9YNbhjTx5R7JzU88JuKEYSXCaeHBUQECX6d-iBG3s8Jjz-cdpjHRfD8Enh2FNDru4oJURITI01x0mzh_YZ-i22X8-rIes9s_v2_OzqvLq78XZ6eXVZBdu1SoaqMNGhANqqZ13mPprwUI4D303ugOopK971BGH6KPDhV4rYJog5dSHrOfe-9M6XHFvNhxyAF3OzdhWrMF04FqGlBQ0B__oA9ppalUZ-sOjJZdrbtCwZ4KlHImjHamYXT0ZEHYLQG7T8CWBOyWgN2K-P5iXv2I_duL15EXoN4DuVxNd0jvX__f-gy4S5LM</recordid><startdate>20180301</startdate><enddate>20180301</enddate><creator>Hirooka, Kazunobu</creator><creator>Oonuki, Masahiro</creator><creator>Manabe, Susumu</creator><creator>Hiraoka, Daisuke</creator><creator>Yasukawa, Takashi</creator><creator>Suzuki, Keiko</creator><general>Springer Japan</general><general>Springer Nature B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>M0S</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0001-7178-2562</orcidid></search><sort><creationdate>20180301</creationdate><title>Radiation therapy for recurrent cardiac undifferentiated pleomorphic sarcoma after three operations</title><author>Hirooka, Kazunobu ; Oonuki, Masahiro ; Manabe, Susumu ; Hiraoka, Daisuke ; Yasukawa, Takashi ; Suzuki, Keiko</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c396t-e42878e8105e456abbe117611c1bb1db8791f43db9e3fbcfbfae41b74c06cb333</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2018</creationdate><topic>Cardiac Surgery</topic><topic>Cardiac Surgical Procedures</topic><topic>Cardiology</topic><topic>Case Report</topic><topic>Chemotherapy</topic><topic>Dose Fractionation</topic><topic>Dyspnea</topic><topic>Female</topic><topic>Heart Atria - pathology</topic><topic>Heart Neoplasms - diagnostic imaging</topic><topic>Heart Neoplasms - radiotherapy</topic><topic>Heart Neoplasms - surgery</topic><topic>Histiocytoma, Malignant Fibrous - diagnostic imaging</topic><topic>Histiocytoma, Malignant Fibrous - radiotherapy</topic><topic>Histiocytoma, Malignant Fibrous - surgery</topic><topic>Humans</topic><topic>Medical prognosis</topic><topic>Medicine</topic><topic>Medicine & Public Health</topic><topic>Metastasis</topic><topic>Middle Aged</topic><topic>Neoplasm Recurrence, Local - diagnostic imaging</topic><topic>Neoplasm Recurrence, Local - radiotherapy</topic><topic>Ostomy</topic><topic>Prostheses</topic><topic>Radiation therapy</topic><topic>Radiotherapy Dosage</topic><topic>Sarcoma</topic><topic>Surgery</topic><topic>Surgical Oncology</topic><topic>Thoracic Surgery</topic><topic>Tomography, X-Ray Computed</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Hirooka, Kazunobu</creatorcontrib><creatorcontrib>Oonuki, Masahiro</creatorcontrib><creatorcontrib>Manabe, Susumu</creatorcontrib><creatorcontrib>Hiraoka, Daisuke</creatorcontrib><creatorcontrib>Yasukawa, Takashi</creatorcontrib><creatorcontrib>Suzuki, Keiko</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>MEDLINE - Academic</collection><jtitle>General thoracic and cardiovascular surgery</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Hirooka, Kazunobu</au><au>Oonuki, Masahiro</au><au>Manabe, Susumu</au><au>Hiraoka, Daisuke</au><au>Yasukawa, Takashi</au><au>Suzuki, Keiko</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Radiation therapy for recurrent cardiac undifferentiated pleomorphic sarcoma after three operations</atitle><jtitle>General thoracic and cardiovascular surgery</jtitle><stitle>Gen Thorac Cardiovasc Surg</stitle><addtitle>Gen Thorac Cardiovasc Surg</addtitle><date>2018-03-01</date><risdate>2018</risdate><volume>66</volume><issue>3</issue><spage>168</spage><epage>171</epage><pages>168-171</pages><issn>1863-6705</issn><eissn>1863-6713</eissn><abstract>We report the case of a 57-year-old female suffering from recurrent malignant undifferentiated pleomorphic sarcoma of the left atrium. Metastasis to the posterior mediastinum was detected upon first presentation. Incomplete resections were carried out twice before mitral valve replacement was finally performed. The tumor recurred 16 months later and was treated with radiation therapy, which has proved to be effective in bringing about tumor regression for 2 years, to date. The patient has survived for 7 years since the first surgery.</abstract><cop>Tokyo</cop><pub>Springer Japan</pub><pmid>28434140</pmid><doi>10.1007/s11748-017-0771-3</doi><tpages>4</tpages><orcidid>https://orcid.org/0000-0001-7178-2562</orcidid></addata></record> |
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subjects | Cardiac Surgery Cardiac Surgical Procedures Cardiology Case Report Chemotherapy Dose Fractionation Dyspnea Female Heart Atria - pathology Heart Neoplasms - diagnostic imaging Heart Neoplasms - radiotherapy Heart Neoplasms - surgery Histiocytoma, Malignant Fibrous - diagnostic imaging Histiocytoma, Malignant Fibrous - radiotherapy Histiocytoma, Malignant Fibrous - surgery Humans Medical prognosis Medicine Medicine & Public Health Metastasis Middle Aged Neoplasm Recurrence, Local - diagnostic imaging Neoplasm Recurrence, Local - radiotherapy Ostomy Prostheses Radiation therapy Radiotherapy Dosage Sarcoma Surgery Surgical Oncology Thoracic Surgery Tomography, X-Ray Computed |
title | Radiation therapy for recurrent cardiac undifferentiated pleomorphic sarcoma after three operations |
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