Fluoride varnishes containing sodium trimetaphosphate reduce enamel demineralization in vitro
Objective: This study evaluated the effects of fluoride varnishes containing sodium trimetaphosphate (TMP) on bovine enamel demineralization in vitro. Material and methods: Enamel bovine discs were randomly assigned into six groups (n = 20/group): placebo, 2.5% NaF, 2.5% NaF/5% TMP, 5% NaF, 5% NaF/5...
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| Veröffentlicht in: | Acta odontologica Scandinavica 2017-07, Vol.75 (5), p.376-378 |
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| container_title | Acta odontologica Scandinavica |
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| creator | Manarelli, Michele M. Delbem, Alberto C. B. Báez-Quintero, Liliana Carolina de Moraes, Felipe Ricardo N. Cunha, Robson F. Pessan, Juliano P. |
| description | Objective: This study evaluated the effects of fluoride varnishes containing sodium trimetaphosphate (TMP) on bovine enamel demineralization in vitro.
Material and methods: Enamel bovine discs were randomly assigned into six groups (n = 20/group): placebo, 2.5% NaF, 2.5% NaF/5% TMP, 5% NaF, 5% NaF/5% TMP, and a commercial formulation (Duraphat, 5% NaF). Varnishes were applied on all enamel discs and kept for 6 h. Loosely and firmly bound fluoride formed on/in enamel after treatment were analyzed in 10 discs from each group. The other 10 discs were subjected to a pH-cycling regimen for 7 days, and analyzed for surface (SH) and cross-sectional hardness (ΔKHN), as well as for loosely and firmly bound fluoride in/on enamel. Data were analyzed by analysis of variance (ANOVA) followed by Student-Newman-Keuls' test (p |
| doi_str_mv | 10.1080/00016357.2017.1318448 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_1891146318</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>1891146318</sourcerecordid><originalsourceid>FETCH-LOGICAL-c366t-2667da29e297aebd0894a571bbf9f495c9f241847cd6a16afbd71e3c914e8dbd3</originalsourceid><addsrcrecordid>eNp9kMFu1DAQhi1ERbeFRwD5yCWLJ3ES-waqWqhUiUs5ImtiT1ijxF5sp6h9-ma1W46cRiN9__yaj7H3ILYglPgkhICuafttLaDfQgNKSvWKbaAVddWoVrxmmwNTHaBzdpHz73WVWuk37LxWsgGpYcN-3kxLTN4Rf8AUfN5R5jaGgj748Ivn6Pwy85L8TAX3u5j3OyzEE7nFEqeAM03c0ewDJZz8ExYfA_eBP_iS4lt2NuKU6d1pXrIfN9f3V9-qu-9fb6--3FW26bpS1V3XO6w11bpHGpxQWmLbwzCMepS6tXqs5fpgb12H0OE4uB6osRokKTe45pJ9PN7dp_hnoVzM7LOlacJAcckGlAaQ3SppRdsjalPMOdFo9utzmB4NCHMwa17MmoNZczK75j6cKpZhJvcv9aJyBT4fAR_GmGb8G9PkTMHHKaYxYbA-m-b_Hc9tfoo9</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1891146318</pqid></control><display><type>article</type><title>Fluoride varnishes containing sodium trimetaphosphate reduce enamel demineralization in vitro</title><source>MEDLINE</source><source>Alma/SFX Local Collection</source><creator>Manarelli, Michele M. ; Delbem, Alberto C. B. ; Báez-Quintero, Liliana Carolina ; de Moraes, Felipe Ricardo N. ; Cunha, Robson F. ; Pessan, Juliano P.</creator><creatorcontrib>Manarelli, Michele M. ; Delbem, Alberto C. B. ; Báez-Quintero, Liliana Carolina ; de Moraes, Felipe Ricardo N. ; Cunha, Robson F. ; Pessan, Juliano P.</creatorcontrib><description>Objective: This study evaluated the effects of fluoride varnishes containing sodium trimetaphosphate (TMP) on bovine enamel demineralization in vitro.
Material and methods: Enamel bovine discs were randomly assigned into six groups (n = 20/group): placebo, 2.5% NaF, 2.5% NaF/5% TMP, 5% NaF, 5% NaF/5% TMP, and a commercial formulation (Duraphat, 5% NaF). Varnishes were applied on all enamel discs and kept for 6 h. Loosely and firmly bound fluoride formed on/in enamel after treatment were analyzed in 10 discs from each group. The other 10 discs were subjected to a pH-cycling regimen for 7 days, and analyzed for surface (SH) and cross-sectional hardness (ΔKHN), as well as for loosely and firmly bound fluoride in/on enamel. Data were analyzed by analysis of variance (ANOVA) followed by Student-Newman-Keuls' test (p < .05).
Results: The lowest SH change and ΔKHN were observed for the 5%NaF/5%TMP varnish, which was significantly different from all the other groups. Both fluoridated varnishes containing TMP promoted significantly lower SH change and ΔKHN when compared with their counterparts without TMP. Loosely and firmly bound fluoride was significantly lower in groups treated with varnishes containing TMP.
Conclusion: TMP and fluoride added to varnishes have a synergistic effect against enamel demineralization in vitro.</description><identifier>ISSN: 0001-6357</identifier><identifier>EISSN: 1502-3850</identifier><identifier>DOI: 10.1080/00016357.2017.1318448</identifier><identifier>PMID: 28431491</identifier><language>eng</language><publisher>England: Taylor & Francis</publisher><subject>Animals ; Cariostatic Agents - pharmacology ; Cariostatic Agents - therapeutic use ; Cattle ; Demineralization ; dental enamel ; Dental Enamel - drug effects ; Dentistry ; Dose-Response Relationship, Drug ; Fluorides - administration & dosage ; Fluorides - pharmacology ; Fluorides, Topical - administration & dosage ; Fluorides, Topical - pharmacology ; fluorine ; Phosphates - pharmacology ; polyphosphates ; Sodium Fluoride - administration & dosage ; Sodium Fluoride - pharmacology ; Tooth Calcification - drug effects ; Tooth Demineralization</subject><ispartof>Acta odontologica Scandinavica, 2017-07, Vol.75 (5), p.376-378</ispartof><rights>2017 Acta Odontologica Scandinavica Society 2017</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c366t-2667da29e297aebd0894a571bbf9f495c9f241847cd6a16afbd71e3c914e8dbd3</citedby><cites>FETCH-LOGICAL-c366t-2667da29e297aebd0894a571bbf9f495c9f241847cd6a16afbd71e3c914e8dbd3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,777,781,27905,27906</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/28431491$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Manarelli, Michele M.</creatorcontrib><creatorcontrib>Delbem, Alberto C. B.</creatorcontrib><creatorcontrib>Báez-Quintero, Liliana Carolina</creatorcontrib><creatorcontrib>de Moraes, Felipe Ricardo N.</creatorcontrib><creatorcontrib>Cunha, Robson F.</creatorcontrib><creatorcontrib>Pessan, Juliano P.</creatorcontrib><title>Fluoride varnishes containing sodium trimetaphosphate reduce enamel demineralization in vitro</title><title>Acta odontologica Scandinavica</title><addtitle>Acta Odontol Scand</addtitle><description>Objective: This study evaluated the effects of fluoride varnishes containing sodium trimetaphosphate (TMP) on bovine enamel demineralization in vitro.
Material and methods: Enamel bovine discs were randomly assigned into six groups (n = 20/group): placebo, 2.5% NaF, 2.5% NaF/5% TMP, 5% NaF, 5% NaF/5% TMP, and a commercial formulation (Duraphat, 5% NaF). Varnishes were applied on all enamel discs and kept for 6 h. Loosely and firmly bound fluoride formed on/in enamel after treatment were analyzed in 10 discs from each group. The other 10 discs were subjected to a pH-cycling regimen for 7 days, and analyzed for surface (SH) and cross-sectional hardness (ΔKHN), as well as for loosely and firmly bound fluoride in/on enamel. Data were analyzed by analysis of variance (ANOVA) followed by Student-Newman-Keuls' test (p < .05).
Results: The lowest SH change and ΔKHN were observed for the 5%NaF/5%TMP varnish, which was significantly different from all the other groups. Both fluoridated varnishes containing TMP promoted significantly lower SH change and ΔKHN when compared with their counterparts without TMP. Loosely and firmly bound fluoride was significantly lower in groups treated with varnishes containing TMP.
Conclusion: TMP and fluoride added to varnishes have a synergistic effect against enamel demineralization in vitro.</description><subject>Animals</subject><subject>Cariostatic Agents - pharmacology</subject><subject>Cariostatic Agents - therapeutic use</subject><subject>Cattle</subject><subject>Demineralization</subject><subject>dental enamel</subject><subject>Dental Enamel - drug effects</subject><subject>Dentistry</subject><subject>Dose-Response Relationship, Drug</subject><subject>Fluorides - administration & dosage</subject><subject>Fluorides - pharmacology</subject><subject>Fluorides, Topical - administration & dosage</subject><subject>Fluorides, Topical - pharmacology</subject><subject>fluorine</subject><subject>Phosphates - pharmacology</subject><subject>polyphosphates</subject><subject>Sodium Fluoride - administration & dosage</subject><subject>Sodium Fluoride - pharmacology</subject><subject>Tooth Calcification - drug effects</subject><subject>Tooth Demineralization</subject><issn>0001-6357</issn><issn>1502-3850</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2017</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kMFu1DAQhi1ERbeFRwD5yCWLJ3ES-waqWqhUiUs5ImtiT1ijxF5sp6h9-ma1W46cRiN9__yaj7H3ILYglPgkhICuafttLaDfQgNKSvWKbaAVddWoVrxmmwNTHaBzdpHz73WVWuk37LxWsgGpYcN-3kxLTN4Rf8AUfN5R5jaGgj748Ivn6Pwy85L8TAX3u5j3OyzEE7nFEqeAM03c0ewDJZz8ExYfA_eBP_iS4lt2NuKU6d1pXrIfN9f3V9-qu-9fb6--3FW26bpS1V3XO6w11bpHGpxQWmLbwzCMepS6tXqs5fpgb12H0OE4uB6osRokKTe45pJ9PN7dp_hnoVzM7LOlacJAcckGlAaQ3SppRdsjalPMOdFo9utzmB4NCHMwa17MmoNZczK75j6cKpZhJvcv9aJyBT4fAR_GmGb8G9PkTMHHKaYxYbA-m-b_Hc9tfoo9</recordid><startdate>20170704</startdate><enddate>20170704</enddate><creator>Manarelli, Michele M.</creator><creator>Delbem, Alberto C. B.</creator><creator>Báez-Quintero, Liliana Carolina</creator><creator>de Moraes, Felipe Ricardo N.</creator><creator>Cunha, Robson F.</creator><creator>Pessan, Juliano P.</creator><general>Taylor & Francis</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20170704</creationdate><title>Fluoride varnishes containing sodium trimetaphosphate reduce enamel demineralization in vitro</title><author>Manarelli, Michele M. ; Delbem, Alberto C. B. ; Báez-Quintero, Liliana Carolina ; de Moraes, Felipe Ricardo N. ; Cunha, Robson F. ; Pessan, Juliano P.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c366t-2667da29e297aebd0894a571bbf9f495c9f241847cd6a16afbd71e3c914e8dbd3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2017</creationdate><topic>Animals</topic><topic>Cariostatic Agents - pharmacology</topic><topic>Cariostatic Agents - therapeutic use</topic><topic>Cattle</topic><topic>Demineralization</topic><topic>dental enamel</topic><topic>Dental Enamel - drug effects</topic><topic>Dentistry</topic><topic>Dose-Response Relationship, Drug</topic><topic>Fluorides - administration & dosage</topic><topic>Fluorides - pharmacology</topic><topic>Fluorides, Topical - administration & dosage</topic><topic>Fluorides, Topical - pharmacology</topic><topic>fluorine</topic><topic>Phosphates - pharmacology</topic><topic>polyphosphates</topic><topic>Sodium Fluoride - administration & dosage</topic><topic>Sodium Fluoride - pharmacology</topic><topic>Tooth Calcification - drug effects</topic><topic>Tooth Demineralization</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Manarelli, Michele M.</creatorcontrib><creatorcontrib>Delbem, Alberto C. B.</creatorcontrib><creatorcontrib>Báez-Quintero, Liliana Carolina</creatorcontrib><creatorcontrib>de Moraes, Felipe Ricardo N.</creatorcontrib><creatorcontrib>Cunha, Robson F.</creatorcontrib><creatorcontrib>Pessan, Juliano P.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Acta odontologica Scandinavica</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Manarelli, Michele M.</au><au>Delbem, Alberto C. B.</au><au>Báez-Quintero, Liliana Carolina</au><au>de Moraes, Felipe Ricardo N.</au><au>Cunha, Robson F.</au><au>Pessan, Juliano P.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Fluoride varnishes containing sodium trimetaphosphate reduce enamel demineralization in vitro</atitle><jtitle>Acta odontologica Scandinavica</jtitle><addtitle>Acta Odontol Scand</addtitle><date>2017-07-04</date><risdate>2017</risdate><volume>75</volume><issue>5</issue><spage>376</spage><epage>378</epage><pages>376-378</pages><issn>0001-6357</issn><eissn>1502-3850</eissn><abstract>Objective: This study evaluated the effects of fluoride varnishes containing sodium trimetaphosphate (TMP) on bovine enamel demineralization in vitro.
Material and methods: Enamel bovine discs were randomly assigned into six groups (n = 20/group): placebo, 2.5% NaF, 2.5% NaF/5% TMP, 5% NaF, 5% NaF/5% TMP, and a commercial formulation (Duraphat, 5% NaF). Varnishes were applied on all enamel discs and kept for 6 h. Loosely and firmly bound fluoride formed on/in enamel after treatment were analyzed in 10 discs from each group. The other 10 discs were subjected to a pH-cycling regimen for 7 days, and analyzed for surface (SH) and cross-sectional hardness (ΔKHN), as well as for loosely and firmly bound fluoride in/on enamel. Data were analyzed by analysis of variance (ANOVA) followed by Student-Newman-Keuls' test (p < .05).
Results: The lowest SH change and ΔKHN were observed for the 5%NaF/5%TMP varnish, which was significantly different from all the other groups. Both fluoridated varnishes containing TMP promoted significantly lower SH change and ΔKHN when compared with their counterparts without TMP. Loosely and firmly bound fluoride was significantly lower in groups treated with varnishes containing TMP.
Conclusion: TMP and fluoride added to varnishes have a synergistic effect against enamel demineralization in vitro.</abstract><cop>England</cop><pub>Taylor & Francis</pub><pmid>28431491</pmid><doi>10.1080/00016357.2017.1318448</doi><tpages>3</tpages></addata></record> |
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| subjects | Animals Cariostatic Agents - pharmacology Cariostatic Agents - therapeutic use Cattle Demineralization dental enamel Dental Enamel - drug effects Dentistry Dose-Response Relationship, Drug Fluorides - administration & dosage Fluorides - pharmacology Fluorides, Topical - administration & dosage Fluorides, Topical - pharmacology fluorine Phosphates - pharmacology polyphosphates Sodium Fluoride - administration & dosage Sodium Fluoride - pharmacology Tooth Calcification - drug effects Tooth Demineralization |
| title | Fluoride varnishes containing sodium trimetaphosphate reduce enamel demineralization in vitro |
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