Rates and predictors of hospital readmission after transcatheter aortic valve implantation
To analyse reasons, timing and predictors of hospital readmissions after transcatheter aortic valve implantation (TAVI). Patients included in the Bern TAVI Registry between August 2007 and June 2014 were analysed. Fine and Gray competing risk regression was used to identify factors predictive of hos...
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Veröffentlicht in: | European heart journal 2017-07, Vol.38 (28), p.2211-2217 |
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creator | Franzone, Anna Pilgrim, Thomas Arnold, Nicolas Heg, Dik Langhammer, Bettina Piccolo, Raffaele Roost, Eva Praz, Fabien Räber, Lorenz Valgimigli, Marco Wenaweser, Peter Jüni, Peter Carrel, Thierry Windecker, Stephan Stortecky, Stefan |
description | To analyse reasons, timing and predictors of hospital readmissions after transcatheter aortic valve implantation (TAVI).
Patients included in the Bern TAVI Registry between August 2007 and June 2014 were analysed. Fine and Gray competing risk regression was used to identify factors predictive of hospital readmission within 1 year after TAVI with bootstrap analysis for internal validation. Of 868 patients alive at discharge, 221 (25.4%) were readmitted within 1 year. Compared with patients not requiring readmission, those with at least one readmission more frequently were male and more often had atrial fibrillation and higher creatinine values (P |
doi_str_mv | 10.1093/eurheartj/ehx182 |
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Patients included in the Bern TAVI Registry between August 2007 and June 2014 were analysed. Fine and Gray competing risk regression was used to identify factors predictive of hospital readmission within 1 year after TAVI with bootstrap analysis for internal validation. Of 868 patients alive at discharge, 221 (25.4%) were readmitted within 1 year. Compared with patients not requiring readmission, those with at least one readmission more frequently were male and more often had atrial fibrillation and higher creatinine values (P < 0.05 for all cases). For overall 308 readmissions, cardiovascular causes accounted for 46.1% with heart failure as the most frequent indication; non-cardiovascular readmissions occurred for surgery (11.7%), gastrointestinal disorders (9.7%), malignancy (4.9%), respiratory diseases (4.6%) and chronic kidney failure (2.6%). Male gender (subhazard ratio, SHR, 1.33, 95% confidence intervals, CI, 1.02-1.73, P = 0.035) and stage 3 kidney injury (SHR 2.04, 95% CI 1.12-3.71, P = 0.021) were found independent risk factors for any hospital readmission, whereas previous myocardial infarction (SHR 1.88, 95% CI 1.22-2.90, P = 0.004) and in-hospital life-threatening bleeding (SHR 2.18, 95%CI 1.24-3.85, P = 0.007) were associated with cardiovascular readmissions. The event rate for mortality was significantly increased after readmissions for any cause (RR 4.29, 95% CI 2.86-6.42, P < 0.001).
Hospital readmission was observed in one out of four patients during the first year after TAVI and was associated with a significant increase in mortality.</description><identifier>ISSN: 0195-668X</identifier><identifier>EISSN: 1522-9645</identifier><identifier>DOI: 10.1093/eurheartj/ehx182</identifier><identifier>PMID: 28430920</identifier><language>eng</language><publisher>England</publisher><subject>Acute Kidney Injury - etiology ; Acute Kidney Injury - mortality ; Aged, 80 and over ; Aortic Valve Stenosis - mortality ; Aortic Valve Stenosis - surgery ; Cardiovascular Diseases - etiology ; Cardiovascular Diseases - mortality ; Female ; Humans ; Length of Stay ; Male ; Patient Readmission - statistics & numerical data ; Postoperative Complications - etiology ; Prognosis ; Prospective Studies ; Registries ; Regression Analysis ; Switzerland - epidemiology ; Transcatheter Aortic Valve Replacement</subject><ispartof>European heart journal, 2017-07, Vol.38 (28), p.2211-2217</ispartof><rights>Published on behalf of the European Society of Cardiology. All rights reserved. © The Author 2017. For permissions, please email: journals.permissions@oup.com.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c407t-2d5f9666aa0fc939220efa1455776d9ee28a2e173bb9412f9f5783b026d69d023</citedby><cites>FETCH-LOGICAL-c407t-2d5f9666aa0fc939220efa1455776d9ee28a2e173bb9412f9f5783b026d69d023</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27901,27902</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/28430920$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Franzone, Anna</creatorcontrib><creatorcontrib>Pilgrim, Thomas</creatorcontrib><creatorcontrib>Arnold, Nicolas</creatorcontrib><creatorcontrib>Heg, Dik</creatorcontrib><creatorcontrib>Langhammer, Bettina</creatorcontrib><creatorcontrib>Piccolo, Raffaele</creatorcontrib><creatorcontrib>Roost, Eva</creatorcontrib><creatorcontrib>Praz, Fabien</creatorcontrib><creatorcontrib>Räber, Lorenz</creatorcontrib><creatorcontrib>Valgimigli, Marco</creatorcontrib><creatorcontrib>Wenaweser, Peter</creatorcontrib><creatorcontrib>Jüni, Peter</creatorcontrib><creatorcontrib>Carrel, Thierry</creatorcontrib><creatorcontrib>Windecker, Stephan</creatorcontrib><creatorcontrib>Stortecky, Stefan</creatorcontrib><title>Rates and predictors of hospital readmission after transcatheter aortic valve implantation</title><title>European heart journal</title><addtitle>Eur Heart J</addtitle><description>To analyse reasons, timing and predictors of hospital readmissions after transcatheter aortic valve implantation (TAVI).
Patients included in the Bern TAVI Registry between August 2007 and June 2014 were analysed. Fine and Gray competing risk regression was used to identify factors predictive of hospital readmission within 1 year after TAVI with bootstrap analysis for internal validation. Of 868 patients alive at discharge, 221 (25.4%) were readmitted within 1 year. Compared with patients not requiring readmission, those with at least one readmission more frequently were male and more often had atrial fibrillation and higher creatinine values (P < 0.05 for all cases). For overall 308 readmissions, cardiovascular causes accounted for 46.1% with heart failure as the most frequent indication; non-cardiovascular readmissions occurred for surgery (11.7%), gastrointestinal disorders (9.7%), malignancy (4.9%), respiratory diseases (4.6%) and chronic kidney failure (2.6%). Male gender (subhazard ratio, SHR, 1.33, 95% confidence intervals, CI, 1.02-1.73, P = 0.035) and stage 3 kidney injury (SHR 2.04, 95% CI 1.12-3.71, P = 0.021) were found independent risk factors for any hospital readmission, whereas previous myocardial infarction (SHR 1.88, 95% CI 1.22-2.90, P = 0.004) and in-hospital life-threatening bleeding (SHR 2.18, 95%CI 1.24-3.85, P = 0.007) were associated with cardiovascular readmissions. The event rate for mortality was significantly increased after readmissions for any cause (RR 4.29, 95% CI 2.86-6.42, P < 0.001).
Hospital readmission was observed in one out of four patients during the first year after TAVI and was associated with a significant increase in mortality.</description><subject>Acute Kidney Injury - etiology</subject><subject>Acute Kidney Injury - mortality</subject><subject>Aged, 80 and over</subject><subject>Aortic Valve Stenosis - mortality</subject><subject>Aortic Valve Stenosis - surgery</subject><subject>Cardiovascular Diseases - etiology</subject><subject>Cardiovascular Diseases - mortality</subject><subject>Female</subject><subject>Humans</subject><subject>Length of Stay</subject><subject>Male</subject><subject>Patient Readmission - statistics & numerical data</subject><subject>Postoperative Complications - etiology</subject><subject>Prognosis</subject><subject>Prospective Studies</subject><subject>Registries</subject><subject>Regression Analysis</subject><subject>Switzerland - epidemiology</subject><subject>Transcatheter Aortic Valve Replacement</subject><issn>0195-668X</issn><issn>1522-9645</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2017</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNo9kEtLxDAUhYMozji6dyVZuqmTpG2aLGXwBQOCKIibctvc0A59maSD_ns7zDiry4XvHA4fIdec3XGm4yWOrkJwYbPE6ocrcULmPBUi0jJJT8mccZ1GUqrPGbnwfsMYU5LLczITKomZFmxOvt4goKfQGTo4NHUZeudpb2nV-6EO0FCHYNra-7rvKNiAjgYHnS8hVLj7oHehLukWmi3Suh0a6AKEib4kZxYaj1eHuyAfjw_vq-do_fr0srpfR2XCshAJk1otpQRgttSxFoKhBZ6kaZZJoxGFAoE8i4tCJ1xYbdNMxQUT0khtmIgX5HbfO7j-e0Qf8mluic00BPvR51xpPtUpvkPZHi1d771Dmw-ubsH95pzlO6P50Wi-NzpFbg7tY9GiOQb-FcZ_uGR2zg</recordid><startdate>20170721</startdate><enddate>20170721</enddate><creator>Franzone, Anna</creator><creator>Pilgrim, Thomas</creator><creator>Arnold, Nicolas</creator><creator>Heg, Dik</creator><creator>Langhammer, Bettina</creator><creator>Piccolo, Raffaele</creator><creator>Roost, Eva</creator><creator>Praz, Fabien</creator><creator>Räber, Lorenz</creator><creator>Valgimigli, Marco</creator><creator>Wenaweser, Peter</creator><creator>Jüni, Peter</creator><creator>Carrel, Thierry</creator><creator>Windecker, Stephan</creator><creator>Stortecky, Stefan</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20170721</creationdate><title>Rates and predictors of hospital readmission after transcatheter aortic valve implantation</title><author>Franzone, Anna ; Pilgrim, Thomas ; Arnold, Nicolas ; Heg, Dik ; Langhammer, Bettina ; Piccolo, Raffaele ; Roost, Eva ; Praz, Fabien ; Räber, Lorenz ; Valgimigli, Marco ; Wenaweser, Peter ; Jüni, Peter ; Carrel, Thierry ; Windecker, Stephan ; Stortecky, Stefan</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c407t-2d5f9666aa0fc939220efa1455776d9ee28a2e173bb9412f9f5783b026d69d023</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2017</creationdate><topic>Acute Kidney Injury - etiology</topic><topic>Acute Kidney Injury - mortality</topic><topic>Aged, 80 and over</topic><topic>Aortic Valve Stenosis - mortality</topic><topic>Aortic Valve Stenosis - surgery</topic><topic>Cardiovascular Diseases - etiology</topic><topic>Cardiovascular Diseases - mortality</topic><topic>Female</topic><topic>Humans</topic><topic>Length of Stay</topic><topic>Male</topic><topic>Patient Readmission - statistics & numerical data</topic><topic>Postoperative Complications - etiology</topic><topic>Prognosis</topic><topic>Prospective Studies</topic><topic>Registries</topic><topic>Regression Analysis</topic><topic>Switzerland - epidemiology</topic><topic>Transcatheter Aortic Valve Replacement</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Franzone, Anna</creatorcontrib><creatorcontrib>Pilgrim, Thomas</creatorcontrib><creatorcontrib>Arnold, Nicolas</creatorcontrib><creatorcontrib>Heg, Dik</creatorcontrib><creatorcontrib>Langhammer, Bettina</creatorcontrib><creatorcontrib>Piccolo, Raffaele</creatorcontrib><creatorcontrib>Roost, Eva</creatorcontrib><creatorcontrib>Praz, Fabien</creatorcontrib><creatorcontrib>Räber, Lorenz</creatorcontrib><creatorcontrib>Valgimigli, Marco</creatorcontrib><creatorcontrib>Wenaweser, Peter</creatorcontrib><creatorcontrib>Jüni, Peter</creatorcontrib><creatorcontrib>Carrel, Thierry</creatorcontrib><creatorcontrib>Windecker, Stephan</creatorcontrib><creatorcontrib>Stortecky, Stefan</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>European heart journal</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Franzone, Anna</au><au>Pilgrim, Thomas</au><au>Arnold, Nicolas</au><au>Heg, Dik</au><au>Langhammer, Bettina</au><au>Piccolo, Raffaele</au><au>Roost, Eva</au><au>Praz, Fabien</au><au>Räber, Lorenz</au><au>Valgimigli, Marco</au><au>Wenaweser, Peter</au><au>Jüni, Peter</au><au>Carrel, Thierry</au><au>Windecker, Stephan</au><au>Stortecky, Stefan</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Rates and predictors of hospital readmission after transcatheter aortic valve implantation</atitle><jtitle>European heart journal</jtitle><addtitle>Eur Heart J</addtitle><date>2017-07-21</date><risdate>2017</risdate><volume>38</volume><issue>28</issue><spage>2211</spage><epage>2217</epage><pages>2211-2217</pages><issn>0195-668X</issn><eissn>1522-9645</eissn><abstract>To analyse reasons, timing and predictors of hospital readmissions after transcatheter aortic valve implantation (TAVI).
Patients included in the Bern TAVI Registry between August 2007 and June 2014 were analysed. Fine and Gray competing risk regression was used to identify factors predictive of hospital readmission within 1 year after TAVI with bootstrap analysis for internal validation. Of 868 patients alive at discharge, 221 (25.4%) were readmitted within 1 year. Compared with patients not requiring readmission, those with at least one readmission more frequently were male and more often had atrial fibrillation and higher creatinine values (P < 0.05 for all cases). For overall 308 readmissions, cardiovascular causes accounted for 46.1% with heart failure as the most frequent indication; non-cardiovascular readmissions occurred for surgery (11.7%), gastrointestinal disorders (9.7%), malignancy (4.9%), respiratory diseases (4.6%) and chronic kidney failure (2.6%). Male gender (subhazard ratio, SHR, 1.33, 95% confidence intervals, CI, 1.02-1.73, P = 0.035) and stage 3 kidney injury (SHR 2.04, 95% CI 1.12-3.71, P = 0.021) were found independent risk factors for any hospital readmission, whereas previous myocardial infarction (SHR 1.88, 95% CI 1.22-2.90, P = 0.004) and in-hospital life-threatening bleeding (SHR 2.18, 95%CI 1.24-3.85, P = 0.007) were associated with cardiovascular readmissions. The event rate for mortality was significantly increased after readmissions for any cause (RR 4.29, 95% CI 2.86-6.42, P < 0.001).
Hospital readmission was observed in one out of four patients during the first year after TAVI and was associated with a significant increase in mortality.</abstract><cop>England</cop><pmid>28430920</pmid><doi>10.1093/eurheartj/ehx182</doi><tpages>7</tpages><oa>free_for_read</oa></addata></record> |
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source | Oxford University Press Journals All Titles (1996-Current); MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; Alma/SFX Local Collection |
subjects | Acute Kidney Injury - etiology Acute Kidney Injury - mortality Aged, 80 and over Aortic Valve Stenosis - mortality Aortic Valve Stenosis - surgery Cardiovascular Diseases - etiology Cardiovascular Diseases - mortality Female Humans Length of Stay Male Patient Readmission - statistics & numerical data Postoperative Complications - etiology Prognosis Prospective Studies Registries Regression Analysis Switzerland - epidemiology Transcatheter Aortic Valve Replacement |
title | Rates and predictors of hospital readmission after transcatheter aortic valve implantation |
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