Evaluation of immune responses of stabilised SAT2 antigens of foot-and-mouth disease in cattle

Abstract Foot-and-mouth disease (FMD) vaccines with improved stability and less reliant on a cold-chain are needed to improve the longevity of immune responses elicited in animals. This is especially so for serotypes O and SAT2 which are unstable in mildly acidic pH conditions or at elevated tempera...

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Veröffentlicht in:	Vaccine 2017-09, Vol.35 (40), p.5426-5433
Hauptverfasser:	Scott, Katherine A, Rathogwa, N.M, Capozzo, A.V, Maree, Francois F
Format:	Artikel
Sprache:	eng
Schlagworte:	Allergy and Immunology Amino Acid Transport System A - immunology Animals Antibodies Antibodies, Neutralizing - immunology Antigens Cattle Combined vaccines Foot & mouth disease Foot-and-Mouth Disease - immunology Foot-and-Mouth Disease - prevention & control Foot-and-mouth disease virus Foot-and-Mouth Disease Virus - immunology Foot-and-Mouth Disease Virus - pathogenicity High temperature Immune response (humoral) Immune system Immunization Immunogenicity Immunoglobulin G Immunology Interferon Lesions Longevity Mutation Neutralization Tests Neutralizing pH effects SAT2 Serotypes Stability Thermostable antigen Vaccines Viral Vaccines - immunology Viral Vaccines - therapeutic use Viruses
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