Zinc Ion Coordinated Poly(Ionic Liquid) Antimicrobial Membranes for Wound Healing
Herein, a series of quaternary ammonium (Qa) or imidazolium (Im) cation-based poly(ionic liquid) (PIL) membranes and their corresponding zinc ion coordinated PIL membranes were synthesized. The effects of chemical structure, including organic cations, alkyl side chain of substitution, and zinc atom...
Gespeichert in:
| Veröffentlicht in: | ACS applied materials & interfaces 2017-05, Vol.9 (17), p.14656-14664 |
|---|---|
| Hauptverfasser: | , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 14664 |
|---|---|
| container_issue | 17 |
| container_start_page | 14656 |
| container_title | ACS applied materials & interfaces |
| container_volume | 9 |
| creator | Xu, Qiming Zheng, Zhiqiang Wang, Bin Mao, Hailei Yan, Feng |
| description | Herein, a series of quaternary ammonium (Qa) or imidazolium (Im) cation-based poly(ionic liquid) (PIL) membranes and their corresponding zinc ion coordinated PIL membranes were synthesized. The effects of chemical structure, including organic cations, alkyl side chain of substitution, and zinc atoms on the antimicrobial activities against Escherichia coli, Staphylococcus aureus, and Candida albicans were investigated. The Zn-containing PIL membranes show higher antibacterial activities compared to those of pristine PIL membranes due to the synergistic attributes of both organic cations (Qa or Im) and zinc atoms. A wound healing test using methicillin-resistant S. aureus infected mouse as the model further demonstrated that zinc ion coordinated PIL membranes were antibacterially active, biologically safe, and may have potential application as an antimicrobial wound dressing in a clinical setting. |
| doi_str_mv | 10.1021/acsami.7b01677 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_1889775504</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>1889775504</sourcerecordid><originalsourceid>FETCH-LOGICAL-a396t-3b881d3eb75d40efc2d9a8993fefe6f18c17ec735be6a691d1aebeb68de8e3bf3</originalsourceid><addsrcrecordid>eNp1kM1LAzEQxYMotlavHiXHKmxN9ivZYylqCxUVFMFLSDazkrK7aZPdQ_97I1t78zTD8HuPNw-ha0pmlMT0XpZeNmbGFKE5YydoTIs0jXicxafHPU1H6ML7DSF5EpPsHI1inlKeZ2SM3r5MW-KVbfHCWqdNKzvQ-NXW-2k4mhKvza43-hbP2840pnRWGVnjZ2iUky14XFmHP23farwEWZv2-xKdVbL2cHWYE_Tx-PC-WEbrl6fVYr6OZFLkXZQozqlOQLFMpwSqMtaF5EWRVFBBXlFeUgYlSzIFucwLqqkEBSrnGjgkqkomaDr4bp3d9eA70RhfQl2HWLb3gnJeMJZlJA3obEBDfO8dVGLrTCPdXlAifmsUQ43iUGMQ3By8e9WAPuJ_vQXgbgCCUGxs79rw6n9uP3BXfeg</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1889775504</pqid></control><display><type>article</type><title>Zinc Ion Coordinated Poly(Ionic Liquid) Antimicrobial Membranes for Wound Healing</title><source>ACS Publications</source><source>MEDLINE</source><creator>Xu, Qiming ; Zheng, Zhiqiang ; Wang, Bin ; Mao, Hailei ; Yan, Feng</creator><creatorcontrib>Xu, Qiming ; Zheng, Zhiqiang ; Wang, Bin ; Mao, Hailei ; Yan, Feng</creatorcontrib><description>Herein, a series of quaternary ammonium (Qa) or imidazolium (Im) cation-based poly(ionic liquid) (PIL) membranes and their corresponding zinc ion coordinated PIL membranes were synthesized. The effects of chemical structure, including organic cations, alkyl side chain of substitution, and zinc atoms on the antimicrobial activities against Escherichia coli, Staphylococcus aureus, and Candida albicans were investigated. The Zn-containing PIL membranes show higher antibacterial activities compared to those of pristine PIL membranes due to the synergistic attributes of both organic cations (Qa or Im) and zinc atoms. A wound healing test using methicillin-resistant S. aureus infected mouse as the model further demonstrated that zinc ion coordinated PIL membranes were antibacterially active, biologically safe, and may have potential application as an antimicrobial wound dressing in a clinical setting.</description><identifier>ISSN: 1944-8244</identifier><identifier>EISSN: 1944-8252</identifier><identifier>DOI: 10.1021/acsami.7b01677</identifier><identifier>PMID: 28418650</identifier><language>eng</language><publisher>United States: American Chemical Society</publisher><subject>Animals ; Anti-Infective Agents ; Ionic Liquids ; Methicillin-Resistant Staphylococcus aureus ; Mice ; Wound Healing ; Zinc - chemistry</subject><ispartof>ACS applied materials & interfaces, 2017-05, Vol.9 (17), p.14656-14664</ispartof><rights>Copyright © 2017 American Chemical Society</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-a396t-3b881d3eb75d40efc2d9a8993fefe6f18c17ec735be6a691d1aebeb68de8e3bf3</citedby><cites>FETCH-LOGICAL-a396t-3b881d3eb75d40efc2d9a8993fefe6f18c17ec735be6a691d1aebeb68de8e3bf3</cites><orcidid>0000-0003-2999-7142 ; 0000-0001-7973-7985 ; 0000-0002-7940-1223 ; 0000-0001-9269-7025 ; 0000-0001-7762-1794</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://pubs.acs.org/doi/pdf/10.1021/acsami.7b01677$$EPDF$$P50$$Gacs$$H</linktopdf><linktohtml>$$Uhttps://pubs.acs.org/doi/10.1021/acsami.7b01677$$EHTML$$P50$$Gacs$$H</linktohtml><link.rule.ids>314,776,780,2752,27053,27901,27902,56713,56763</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/28418650$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Xu, Qiming</creatorcontrib><creatorcontrib>Zheng, Zhiqiang</creatorcontrib><creatorcontrib>Wang, Bin</creatorcontrib><creatorcontrib>Mao, Hailei</creatorcontrib><creatorcontrib>Yan, Feng</creatorcontrib><title>Zinc Ion Coordinated Poly(Ionic Liquid) Antimicrobial Membranes for Wound Healing</title><title>ACS applied materials & interfaces</title><addtitle>ACS Appl. Mater. Interfaces</addtitle><description>Herein, a series of quaternary ammonium (Qa) or imidazolium (Im) cation-based poly(ionic liquid) (PIL) membranes and their corresponding zinc ion coordinated PIL membranes were synthesized. The effects of chemical structure, including organic cations, alkyl side chain of substitution, and zinc atoms on the antimicrobial activities against Escherichia coli, Staphylococcus aureus, and Candida albicans were investigated. The Zn-containing PIL membranes show higher antibacterial activities compared to those of pristine PIL membranes due to the synergistic attributes of both organic cations (Qa or Im) and zinc atoms. A wound healing test using methicillin-resistant S. aureus infected mouse as the model further demonstrated that zinc ion coordinated PIL membranes were antibacterially active, biologically safe, and may have potential application as an antimicrobial wound dressing in a clinical setting.</description><subject>Animals</subject><subject>Anti-Infective Agents</subject><subject>Ionic Liquids</subject><subject>Methicillin-Resistant Staphylococcus aureus</subject><subject>Mice</subject><subject>Wound Healing</subject><subject>Zinc - chemistry</subject><issn>1944-8244</issn><issn>1944-8252</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2017</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp1kM1LAzEQxYMotlavHiXHKmxN9ivZYylqCxUVFMFLSDazkrK7aZPdQ_97I1t78zTD8HuPNw-ha0pmlMT0XpZeNmbGFKE5YydoTIs0jXicxafHPU1H6ML7DSF5EpPsHI1inlKeZ2SM3r5MW-KVbfHCWqdNKzvQ-NXW-2k4mhKvza43-hbP2840pnRWGVnjZ2iUky14XFmHP23farwEWZv2-xKdVbL2cHWYE_Tx-PC-WEbrl6fVYr6OZFLkXZQozqlOQLFMpwSqMtaF5EWRVFBBXlFeUgYlSzIFucwLqqkEBSrnGjgkqkomaDr4bp3d9eA70RhfQl2HWLb3gnJeMJZlJA3obEBDfO8dVGLrTCPdXlAifmsUQ43iUGMQ3By8e9WAPuJ_vQXgbgCCUGxs79rw6n9uP3BXfeg</recordid><startdate>20170503</startdate><enddate>20170503</enddate><creator>Xu, Qiming</creator><creator>Zheng, Zhiqiang</creator><creator>Wang, Bin</creator><creator>Mao, Hailei</creator><creator>Yan, Feng</creator><general>American Chemical Society</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0003-2999-7142</orcidid><orcidid>https://orcid.org/0000-0001-7973-7985</orcidid><orcidid>https://orcid.org/0000-0002-7940-1223</orcidid><orcidid>https://orcid.org/0000-0001-9269-7025</orcidid><orcidid>https://orcid.org/0000-0001-7762-1794</orcidid></search><sort><creationdate>20170503</creationdate><title>Zinc Ion Coordinated Poly(Ionic Liquid) Antimicrobial Membranes for Wound Healing</title><author>Xu, Qiming ; Zheng, Zhiqiang ; Wang, Bin ; Mao, Hailei ; Yan, Feng</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-a396t-3b881d3eb75d40efc2d9a8993fefe6f18c17ec735be6a691d1aebeb68de8e3bf3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2017</creationdate><topic>Animals</topic><topic>Anti-Infective Agents</topic><topic>Ionic Liquids</topic><topic>Methicillin-Resistant Staphylococcus aureus</topic><topic>Mice</topic><topic>Wound Healing</topic><topic>Zinc - chemistry</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Xu, Qiming</creatorcontrib><creatorcontrib>Zheng, Zhiqiang</creatorcontrib><creatorcontrib>Wang, Bin</creatorcontrib><creatorcontrib>Mao, Hailei</creatorcontrib><creatorcontrib>Yan, Feng</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>ACS applied materials & interfaces</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Xu, Qiming</au><au>Zheng, Zhiqiang</au><au>Wang, Bin</au><au>Mao, Hailei</au><au>Yan, Feng</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Zinc Ion Coordinated Poly(Ionic Liquid) Antimicrobial Membranes for Wound Healing</atitle><jtitle>ACS applied materials & interfaces</jtitle><addtitle>ACS Appl. Mater. Interfaces</addtitle><date>2017-05-03</date><risdate>2017</risdate><volume>9</volume><issue>17</issue><spage>14656</spage><epage>14664</epage><pages>14656-14664</pages><issn>1944-8244</issn><eissn>1944-8252</eissn><abstract>Herein, a series of quaternary ammonium (Qa) or imidazolium (Im) cation-based poly(ionic liquid) (PIL) membranes and their corresponding zinc ion coordinated PIL membranes were synthesized. The effects of chemical structure, including organic cations, alkyl side chain of substitution, and zinc atoms on the antimicrobial activities against Escherichia coli, Staphylococcus aureus, and Candida albicans were investigated. The Zn-containing PIL membranes show higher antibacterial activities compared to those of pristine PIL membranes due to the synergistic attributes of both organic cations (Qa or Im) and zinc atoms. A wound healing test using methicillin-resistant S. aureus infected mouse as the model further demonstrated that zinc ion coordinated PIL membranes were antibacterially active, biologically safe, and may have potential application as an antimicrobial wound dressing in a clinical setting.</abstract><cop>United States</cop><pub>American Chemical Society</pub><pmid>28418650</pmid><doi>10.1021/acsami.7b01677</doi><tpages>9</tpages><orcidid>https://orcid.org/0000-0003-2999-7142</orcidid><orcidid>https://orcid.org/0000-0001-7973-7985</orcidid><orcidid>https://orcid.org/0000-0002-7940-1223</orcidid><orcidid>https://orcid.org/0000-0001-9269-7025</orcidid><orcidid>https://orcid.org/0000-0001-7762-1794</orcidid></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1944-8244 |
| ispartof | ACS applied materials & interfaces, 2017-05, Vol.9 (17), p.14656-14664 |
| issn | 1944-8244 1944-8252 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_1889775504 |
| source | ACS Publications; MEDLINE |
| subjects | Animals Anti-Infective Agents Ionic Liquids Methicillin-Resistant Staphylococcus aureus Mice Wound Healing Zinc - chemistry |
| title | Zinc Ion Coordinated Poly(Ionic Liquid) Antimicrobial Membranes for Wound Healing |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-30T06%3A10%3A01IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Zinc%20Ion%20Coordinated%20Poly(Ionic%20Liquid)%20Antimicrobial%20Membranes%20for%20Wound%20Healing&rft.jtitle=ACS%20applied%20materials%20&%20interfaces&rft.au=Xu,%20Qiming&rft.date=2017-05-03&rft.volume=9&rft.issue=17&rft.spage=14656&rft.epage=14664&rft.pages=14656-14664&rft.issn=1944-8244&rft.eissn=1944-8252&rft_id=info:doi/10.1021/acsami.7b01677&rft_dat=%3Cproquest_cross%3E1889775504%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1889775504&rft_id=info:pmid/28418650&rfr_iscdi=true |