The Laminin Binding Protein p40 Is Involved in Inducing Limb Abnormality of Mouse Fetuses as the Effects of Methoxyacetic Acid Treatment

This study is intended to characterize a protein that is linked with mouse limb teratogenicity as the effects of methoxyacetic acid (MAA) treatment. A single dose of MAA (10 mmol/kg body weight) was given by gavage on gestation day (GD) 11, whereas the control group were administered vehicle only. T...

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Veröffentlicht in:	Toxicological sciences 2003-09, Vol.75 (1), p.148-153
Hauptverfasser:	Ruyani, Aceng, Sudarwati, Sri, Sutasurya, Lien A., Sumarsono, Sony H., Gloe, Torsten
Format:	Artikel
Sprache:	eng
Schlagworte:	2-D SDS–PAGE Acetates - toxicity Amino Acid Sequence Animals Biological and medical sciences Blotting, Western Carrier Proteins - chemistry Carrier Proteins - metabolism Electrophoresis Electrophoresis, Polyacrylamide Gel Embryology: invertebrates and vertebrates. Teratology Embryonic and Fetal Development - drug effects Female Forelimb - abnormalities Forelimb - embryology Forelimb - metabolism Fundamental and applied biological sciences. Psychology Laminin - metabolism LBP-p40 limb teratogenicity Male methoxyacetic acid Mice Molecular Sequence Data Pregnancy Teratology. Teratogens
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