Polyamine sensitization in offshore workers handling drilling muds

Oil‐based mud, a complex mixture containing amines in emulsifiers, is used in offshore drilling operations. It is a skin irritant that occasionally gives rise to allergic contact sensitivity. In patch testing patients with allergy to drilling mud, we have identified polyamine (diethylentriamine and...

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Veröffentlicht in:Contact dermatitis 1989-11, Vol.21 (5), p.326-329
Hauptverfasser: Ormerod, A. D., Wakeel, R. A., Mann, T. A. N., Main, R. A., Aldiridge, R. D.
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container_end_page 329
container_issue 5
container_start_page 326
container_title Contact dermatitis
container_volume 21
creator Ormerod, A. D.
Wakeel, R. A.
Mann, T. A. N.
Main, R. A.
Aldiridge, R. D.
description Oil‐based mud, a complex mixture containing amines in emulsifiers, is used in offshore drilling operations. It is a skin irritant that occasionally gives rise to allergic contact sensitivity. In patch testing patients with allergy to drilling mud, we have identified polyamine (diethylentriamine and triethylentetramine) sensitivity in patients. All 5 patients were also allergic to emulsifiers. These emulsifiers are cross‐linked fatty acid amido‐amines, in which unreacted aimine groups are thought to cross‐sensitized with these constitutent polyamines. Cross‐reactivity between ethylenediamine, diethylenetetramine and triethylenertetramine polyamines. Cross‐reactivity between ethulenediamine, diethyllenetetramine and triethylenetetramine was found in 9 subjects.
doi_str_mv 10.1111/j.1600-0536.1989.tb04752.x
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Cross‐reactivity between ethylenediamine, diethylenetetramine and triethylenertetramine polyamines. Cross‐reactivity between ethulenediamine, diethyllenetetramine and triethylenetetramine was found in 9 subjects.</description><subject>Adult</subject><subject>allergic contact dermatitis</subject><subject>Allergic diseases</subject><subject>Biological and medical sciences</subject><subject>Chemical Industry</subject><subject>Dermatitis, Contact - etiology</subject><subject>Dermatitis, Occupational - chemically induced</subject><subject>diethylenetriamine</subject><subject>drilling fluid</subject><subject>Emulsions - adverse effects</subject><subject>ethylenediamine</subject><subject>Ethylenediamines - adverse effects</subject><subject>Humans</subject><subject>Immunopathology</subject><subject>irritant contact dermatitis</subject><subject>Lubrication</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Mineral Oil - adverse effects</subject><subject>North Sea</subject><subject>occupational</subject><subject>oil and gas industry</subject><subject>oil based mud</subject><subject>Petroleum</subject><subject>Polyamines - adverse effects</subject><subject>Skin allergic diseases. 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D.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4706-488152eb11ca2094f2ce003f9a7a1704413399c6f142f17e57d70b8cb8138413</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1989</creationdate><topic>Adult</topic><topic>allergic contact dermatitis</topic><topic>Allergic diseases</topic><topic>Biological and medical sciences</topic><topic>Chemical Industry</topic><topic>Dermatitis, Contact - etiology</topic><topic>Dermatitis, Occupational - chemically induced</topic><topic>diethylenetriamine</topic><topic>drilling fluid</topic><topic>Emulsions - adverse effects</topic><topic>ethylenediamine</topic><topic>Ethylenediamines - adverse effects</topic><topic>Humans</topic><topic>Immunopathology</topic><topic>irritant contact dermatitis</topic><topic>Lubrication</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Mineral Oil - adverse effects</topic><topic>North Sea</topic><topic>occupational</topic><topic>oil and gas industry</topic><topic>oil based mud</topic><topic>Petroleum</topic><topic>Polyamines - adverse effects</topic><topic>Skin allergic diseases. Stinging insect allergies</topic><topic>Trientine - adverse effects</topic><topic>triethylnetetramine</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Ormerod, A. D.</creatorcontrib><creatorcontrib>Wakeel, R. A.</creatorcontrib><creatorcontrib>Mann, T. A. N.</creatorcontrib><creatorcontrib>Main, R. A.</creatorcontrib><creatorcontrib>Aldiridge, R. D.</creatorcontrib><collection>Istex</collection><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Immunology Abstracts</collection><collection>AIDS and Cancer Research Abstracts</collection><jtitle>Contact dermatitis</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Ormerod, A. 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These emulsifiers are cross‐linked fatty acid amido‐amines, in which unreacted aimine groups are thought to cross‐sensitized with these constitutent polyamines. Cross‐reactivity between ethylenediamine, diethylenetetramine and triethylenertetramine polyamines. Cross‐reactivity between ethulenediamine, diethyllenetetramine and triethylenetetramine was found in 9 subjects.</abstract><cop>Oxford, UK</cop><pub>Blackwell Publishing Ltd</pub><pmid>2533536</pmid><doi>10.1111/j.1600-0536.1989.tb04752.x</doi><tpages>4</tpages></addata></record>
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subjects Adult
allergic contact dermatitis
Allergic diseases
Biological and medical sciences
Chemical Industry
Dermatitis, Contact - etiology
Dermatitis, Occupational - chemically induced
diethylenetriamine
drilling fluid
Emulsions - adverse effects
ethylenediamine
Ethylenediamines - adverse effects
Humans
Immunopathology
irritant contact dermatitis
Lubrication
Male
Medical sciences
Middle Aged
Mineral Oil - adverse effects
North Sea
occupational
oil and gas industry
oil based mud
Petroleum
Polyamines - adverse effects
Skin allergic diseases. Stinging insect allergies
Trientine - adverse effects
triethylnetetramine
title Polyamine sensitization in offshore workers handling drilling muds
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