Different skin irritation abilities of different qualities of sodium lauryl sulphate
A marked variation in the concentration of sodium lauryl sulphate (SLS) used for irritant patch testing is found in the literature, but is hitherto unexplained. In the present study, 2 different qualities of SLS were tested clinically on healthy volunteers. The skin responses were evaluated by visua...
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| Veröffentlicht in: | Contact dermatitis 1989-09, Vol.21 (3), p.184-188 |
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| container_title | Contact dermatitis |
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| creator | Agner, Tove Serup, Jørgen Handlos, Vagn Batsberg, Walther |
| description | A marked variation in the concentration of sodium lauryl sulphate (SLS) used for irritant patch testing is found in the literature, but is hitherto unexplained. In the present study, 2 different qualities of SLS were tested clinically on healthy volunteers. The skin responses were evaluated by visual scoring as well as by non‐invasive measurement of transepidermal water loss (TEWL). blood flow and oedema. A significant difference in the skin response lo the 2 qualities was found both clinically and by non‐invasive methods used for quantitation. 5 different qualities of SLS were investigated by high‐performance liquid chromatography (HPLC). Marked discrepancies in the quantity of C12 carbon chains in the products were found, offering an explanation for the proven difference in the clinical response. It is concluded that only SLS qualities of high purity should be used for irritant patch testing, and that both the quality and the purity of SLS should be slated. |
| doi_str_mv | 10.1111/j.1600-0536.1989.tb04733.x |
| format | Article |
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In the present study, 2 different qualities of SLS were tested clinically on healthy volunteers. The skin responses were evaluated by visual scoring as well as by non‐invasive measurement of transepidermal water loss (TEWL). blood flow and oedema. A significant difference in the skin response lo the 2 qualities was found both clinically and by non‐invasive methods used for quantitation. 5 different qualities of SLS were investigated by high‐performance liquid chromatography (HPLC). Marked discrepancies in the quantity of C12 carbon chains in the products were found, offering an explanation for the proven difference in the clinical response. It is concluded that only SLS qualities of high purity should be used for irritant patch testing, and that both the quality and the purity of SLS should be slated.</description><identifier>ISSN: 0105-1873</identifier><identifier>EISSN: 1600-0536</identifier><identifier>DOI: 10.1111/j.1600-0536.1989.tb04733.x</identifier><identifier>PMID: 2791543</identifier><identifier>CODEN: CODEDG</identifier><language>eng</language><publisher>Oxford, UK: Blackwell Publishing Ltd</publisher><subject>Adult ; Allergic diseases ; Biological and medical sciences ; Chromatography, High Pressure Liquid ; Dermatitis, Contact - etiology ; different commercial sources ; Female ; high-performance liquid chromatography ; Humans ; Immunopathology ; irritation ; Male ; Medical sciences ; patch testing ; purity ; quality ; Skin allergic diseases. Stinging insect allergies ; Skin Tests ; Sodium Dodecyl Sulfate - adverse effects ; Sodium Dodecyl Sulfate - immunology ; sodium lauryl sulphate</subject><ispartof>Contact dermatitis, 1989-09, Vol.21 (3), p.184-188</ispartof><rights>1989 John Wiley & Sons A/S. 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In the present study, 2 different qualities of SLS were tested clinically on healthy volunteers. The skin responses were evaluated by visual scoring as well as by non‐invasive measurement of transepidermal water loss (TEWL). blood flow and oedema. A significant difference in the skin response lo the 2 qualities was found both clinically and by non‐invasive methods used for quantitation. 5 different qualities of SLS were investigated by high‐performance liquid chromatography (HPLC). Marked discrepancies in the quantity of C12 carbon chains in the products were found, offering an explanation for the proven difference in the clinical response. It is concluded that only SLS qualities of high purity should be used for irritant patch testing, and that both the quality and the purity of SLS should be slated.</description><subject>Adult</subject><subject>Allergic diseases</subject><subject>Biological and medical sciences</subject><subject>Chromatography, High Pressure Liquid</subject><subject>Dermatitis, Contact - etiology</subject><subject>different commercial sources</subject><subject>Female</subject><subject>high-performance liquid chromatography</subject><subject>Humans</subject><subject>Immunopathology</subject><subject>irritation</subject><subject>Male</subject><subject>Medical sciences</subject><subject>patch testing</subject><subject>purity</subject><subject>quality</subject><subject>Skin allergic diseases. Stinging insect allergies</subject><subject>Skin Tests</subject><subject>Sodium Dodecyl Sulfate - adverse effects</subject><subject>Sodium Dodecyl Sulfate - immunology</subject><subject>sodium lauryl sulphate</subject><issn>0105-1873</issn><issn>1600-0536</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1989</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqVkFtr2zAYhkVp6dJsP6FgSi92Y08n69CLQUlPg9BeLKOXQpJlplSxU8lmyb-vQ4x3Xd0I9L7f84kHgCsECzScH-sCMQhzWBJWIClk0RlIOSHF7gTMpugUzCCCZY4EJ1_ARUprCBGjWJyDc8wlKimZgdWdr2sXXdNl6c03mY_Rd7rzbZNp44PvvEtZW2fVVHvv9f_n1Fa-32RB93EfstSH7V_dua_grNYhuW_jPQd_Hu5Xi6d8-fL4a3G7zC1lkuaSS2E4lEgba6hgRBOLGMKMQULgkDlrKyO1lJxTiiHElJqKkhoKgQ0WZA6-H7nb2L73LnVq45N1IejGtX1SSAghmaAcD9WbY9XGNqXoarWNfqPjXiGoDlLVWh3MqYM5dZCqRqlqNwxfjnt6s3HVNDpaHPLrMdfJ6lBH3VifphorBSIDdw5-Hmv_fHD7T3xALV7ukKADID8CfOrcbgLo-KYYJ7xUr8-PCovfCL0uV2pBPgA32qJZ</recordid><startdate>198909</startdate><enddate>198909</enddate><creator>Agner, Tove</creator><creator>Serup, Jørgen</creator><creator>Handlos, Vagn</creator><creator>Batsberg, Walther</creator><general>Blackwell Publishing Ltd</general><general>Blackwell</general><scope>BSCLL</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7T5</scope><scope>H94</scope></search><sort><creationdate>198909</creationdate><title>Different skin irritation abilities of different qualities of sodium lauryl sulphate</title><author>Agner, Tove ; Serup, Jørgen ; Handlos, Vagn ; Batsberg, Walther</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4694-9798b7091abcb4863a3c161266033098beccdb9a997744200244bd43f0882b283</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1989</creationdate><topic>Adult</topic><topic>Allergic diseases</topic><topic>Biological and medical sciences</topic><topic>Chromatography, High Pressure Liquid</topic><topic>Dermatitis, Contact - etiology</topic><topic>different commercial sources</topic><topic>Female</topic><topic>high-performance liquid chromatography</topic><topic>Humans</topic><topic>Immunopathology</topic><topic>irritation</topic><topic>Male</topic><topic>Medical sciences</topic><topic>patch testing</topic><topic>purity</topic><topic>quality</topic><topic>Skin allergic diseases. Stinging insect allergies</topic><topic>Skin Tests</topic><topic>Sodium Dodecyl Sulfate - adverse effects</topic><topic>Sodium Dodecyl Sulfate - immunology</topic><topic>sodium lauryl sulphate</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Agner, Tove</creatorcontrib><creatorcontrib>Serup, Jørgen</creatorcontrib><creatorcontrib>Handlos, Vagn</creatorcontrib><creatorcontrib>Batsberg, Walther</creatorcontrib><collection>Istex</collection><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Immunology Abstracts</collection><collection>AIDS and Cancer Research Abstracts</collection><jtitle>Contact dermatitis</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Agner, Tove</au><au>Serup, Jørgen</au><au>Handlos, Vagn</au><au>Batsberg, Walther</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Different skin irritation abilities of different qualities of sodium lauryl sulphate</atitle><jtitle>Contact dermatitis</jtitle><addtitle>Contact Dermatitis</addtitle><date>1989-09</date><risdate>1989</risdate><volume>21</volume><issue>3</issue><spage>184</spage><epage>188</epage><pages>184-188</pages><issn>0105-1873</issn><eissn>1600-0536</eissn><coden>CODEDG</coden><abstract>A marked variation in the concentration of sodium lauryl sulphate (SLS) used for irritant patch testing is found in the literature, but is hitherto unexplained. In the present study, 2 different qualities of SLS were tested clinically on healthy volunteers. The skin responses were evaluated by visual scoring as well as by non‐invasive measurement of transepidermal water loss (TEWL). blood flow and oedema. A significant difference in the skin response lo the 2 qualities was found both clinically and by non‐invasive methods used for quantitation. 5 different qualities of SLS were investigated by high‐performance liquid chromatography (HPLC). Marked discrepancies in the quantity of C12 carbon chains in the products were found, offering an explanation for the proven difference in the clinical response. It is concluded that only SLS qualities of high purity should be used for irritant patch testing, and that both the quality and the purity of SLS should be slated.</abstract><cop>Oxford, UK</cop><pub>Blackwell Publishing Ltd</pub><pmid>2791543</pmid><doi>10.1111/j.1600-0536.1989.tb04733.x</doi><tpages>5</tpages></addata></record> |
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| ispartof | Contact dermatitis, 1989-09, Vol.21 (3), p.184-188 |
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| language | eng |
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| source | MEDLINE; Wiley Online Library Journals Frontfile Complete |
| subjects | Adult Allergic diseases Biological and medical sciences Chromatography, High Pressure Liquid Dermatitis, Contact - etiology different commercial sources Female high-performance liquid chromatography Humans Immunopathology irritation Male Medical sciences patch testing purity quality Skin allergic diseases. Stinging insect allergies Skin Tests Sodium Dodecyl Sulfate - adverse effects Sodium Dodecyl Sulfate - immunology sodium lauryl sulphate |
| title | Different skin irritation abilities of different qualities of sodium lauryl sulphate |
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