Investigation of correlations between DNA methylation, suicidal behavior and aging

Objectives Suicidal behavior (SB) is a major cause of mortality for patients diagnosed with bipolar disorder (BD). In this study, we investigated epigenetic differences in BD participants with and without a history of SB. Methods We used suicidality scores constructed from Schedule for Clinical Asse...

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Veröffentlicht in:	Bipolar disorders 2017-02, Vol.19 (1), p.32-40
Hauptverfasser:	Jeremian, Richie, Chen, Yi‐an, De Luca, Vincenzo, Vincent, John B, Kennedy, James L, Zai, Clement C, Strauss, John
Format:	Artikel
Sprache:	eng
Schlagworte:	450K 5' Untranslated Regions Adult Age Aging Aging - genetics Bipolar disorder Bipolar Disorder - complications Bipolar Disorder - genetics Bipolar Disorder - psychology Deoxyribonucleic acid DNA DNA methylation DNA Methylation - genetics DNA microarrays Epigenesis, Genetic Epigenetics Eye Proteins - genetics Female GTPase-Activating Proteins - genetics Humans Male Membrane proteins Membrane Proteins - genetics Middle Aged Minor Histocompatibility Antigens - genetics Nuclear Pore Complex Proteins - genetics Nucleoside-Phosphate Kinase - genetics Regulatory sequences Risk Assessment - methods Suicidal behavior Suicidal Ideation Suicide Suicide - prevention & control Suicide - psychology Suicides & suicide attempts
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