Glioblastoma Multiforme and Adult Neurogenesis in the Ventricular‐Subventricular Zone: A Review
Brain cancers account for
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| Veröffentlicht in: | Journal of cellular physiology 2017-07, Vol.232 (7), p.1596-1601 |
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| container_issue | 7 |
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| container_title | Journal of cellular physiology |
| container_volume | 232 |
| creator | Capdevila, Claudia Rodríguez Vázquez, Lucía Martí, Joaquín |
| description | Brain cancers account for |
| doi_str_mv | 10.1002/jcp.25502 |
| format | Article |
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Glioblastoma multiforme are the most common and lethal primary tumors of the central nervous system. We focus on the link between neural stem cells in the ventricular‐subventricular zone, and the initiation and development of the glioblastoma multiforme.</description><identifier>ISSN: 0021-9541</identifier><identifier>EISSN: 1097-4652</identifier><identifier>DOI: 10.1002/jcp.25502</identifier><identifier>PMID: 27458813</identifier><language>eng</language><publisher>United States: Wiley Subscription Services, Inc</publisher><subject>Central nervous system ; Glioblastoma - pathology ; Humans ; Hypoxia ; Lateral Ventricles - pathology ; Models, Biological ; Neurogenesis ; Stem cells ; Tumor Microenvironment</subject><ispartof>Journal of cellular physiology, 2017-07, Vol.232 (7), p.1596-1601</ispartof><rights>2016 Wiley Periodicals, Inc.</rights><rights>2017 Wiley Periodicals, Inc.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c3862-81581f9d49c9a63867d1a4d6876af3b34e53751d65aa69d5e647cc50d932b9a23</citedby><cites>FETCH-LOGICAL-c3862-81581f9d49c9a63867d1a4d6876af3b34e53751d65aa69d5e647cc50d932b9a23</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1002%2Fjcp.25502$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1002%2Fjcp.25502$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,780,784,1416,27922,27923,45572,45573</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/27458813$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Capdevila, Claudia</creatorcontrib><creatorcontrib>Rodríguez Vázquez, Lucía</creatorcontrib><creatorcontrib>Martí, Joaquín</creatorcontrib><title>Glioblastoma Multiforme and Adult Neurogenesis in the Ventricular‐Subventricular Zone: A Review</title><title>Journal of cellular physiology</title><addtitle>J Cell Physiol</addtitle><description>Brain cancers account for <1,5% of all new cancer cases reported in the United States each year. Due to their invasive and heterogeneous nature, in addition to their resistance to multimodal treatments, these tumors are usually fatal. Gliomas, and in particular high‐grade astrocytomas such as glioblastoma multiforme (GBM), are the most common and lethal primary tumors of the central nervous system. The median survival of most patients is less than 1 year after application of multimodal therapies. The question is why are these cancers so injurious? And above all, how is it possible for a so carefully orchestrated area like the brain to develop such tumors? This brings us to the study of glioma stem cells, their specialized niches (perivascular and hypoxic), and the neurogenic phenomena that takes place within the adult ventricular‐subventricular zone: a structure that lies at the intersection between brain development and gliomagenesis. J. Cell. Physiol. 232: 1596–1601, 2017. © 2016 Wiley Periodicals, Inc.
Glioblastoma multiforme are the most common and lethal primary tumors of the central nervous system. We focus on the link between neural stem cells in the ventricular‐subventricular zone, and the initiation and development of the glioblastoma multiforme.</description><subject>Central nervous system</subject><subject>Glioblastoma - pathology</subject><subject>Humans</subject><subject>Hypoxia</subject><subject>Lateral Ventricles - pathology</subject><subject>Models, Biological</subject><subject>Neurogenesis</subject><subject>Stem cells</subject><subject>Tumor Microenvironment</subject><issn>0021-9541</issn><issn>1097-4652</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2017</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqN0c9OFTEUBvCGSOSCLnwB0sQNLgb6f1p3NzeIGkCj4sLNpDM9g72ZmV7aGQg7HoFn9EksXITExMTVSU9_-ZKTD6FXlOxTQtjBslntMykJ20AzSkxZCCXZMzTLf7QwUtAttJ3SkhBiDOfP0RYrhdSa8hmyR50PdWfTGHqLT6Zu9G2IPWA7ODx3-Y1PYYrhHAZIPmE_4PEn4O8wjNE3U2fjr5vbr1N9-bTAP8IAb_Ecf4FLD1cv0GZruwQvH-YOOnt3-G3xvjj-dPRhMT8uGq4VKzSVmrbGCdMYq_KqdNQKp3SpbMtrLkDyUlKnpLXKOAlKlE0jiTOc1cYyvoP21rmrGC4mSGPV-9RA19kBwpQqqrU2UjLxP5SpkhN-T1__RZdhikM-5C6QiqyUzurNWjUxpBShrVbR9zZeV5RUdxVVuaLqvqJsdx8Sp7oH9yj_dJLBwRpc-Q6u_51UfVx8Xkf-Bqtimj4</recordid><startdate>201707</startdate><enddate>201707</enddate><creator>Capdevila, Claudia</creator><creator>Rodríguez Vázquez, Lucía</creator><creator>Martí, Joaquín</creator><general>Wiley Subscription Services, Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7TK</scope><scope>7U7</scope><scope>8FD</scope><scope>C1K</scope><scope>FR3</scope><scope>K9.</scope><scope>P64</scope><scope>RC3</scope><scope>7X8</scope></search><sort><creationdate>201707</creationdate><title>Glioblastoma Multiforme and Adult Neurogenesis in the Ventricular‐Subventricular Zone: A Review</title><author>Capdevila, Claudia ; Rodríguez Vázquez, Lucía ; Martí, Joaquín</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3862-81581f9d49c9a63867d1a4d6876af3b34e53751d65aa69d5e647cc50d932b9a23</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2017</creationdate><topic>Central nervous system</topic><topic>Glioblastoma - pathology</topic><topic>Humans</topic><topic>Hypoxia</topic><topic>Lateral Ventricles - pathology</topic><topic>Models, Biological</topic><topic>Neurogenesis</topic><topic>Stem cells</topic><topic>Tumor Microenvironment</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Capdevila, Claudia</creatorcontrib><creatorcontrib>Rodríguez Vázquez, Lucía</creatorcontrib><creatorcontrib>Martí, Joaquín</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Neurosciences Abstracts</collection><collection>Toxicology Abstracts</collection><collection>Technology Research Database</collection><collection>Environmental Sciences and Pollution Management</collection><collection>Engineering Research Database</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>Genetics Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of cellular physiology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Capdevila, Claudia</au><au>Rodríguez Vázquez, Lucía</au><au>Martí, Joaquín</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Glioblastoma Multiforme and Adult Neurogenesis in the Ventricular‐Subventricular Zone: A Review</atitle><jtitle>Journal of cellular physiology</jtitle><addtitle>J Cell Physiol</addtitle><date>2017-07</date><risdate>2017</risdate><volume>232</volume><issue>7</issue><spage>1596</spage><epage>1601</epage><pages>1596-1601</pages><issn>0021-9541</issn><eissn>1097-4652</eissn><abstract>Brain cancers account for <1,5% of all new cancer cases reported in the United States each year. 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| ispartof | Journal of cellular physiology, 2017-07, Vol.232 (7), p.1596-1601 |
| issn | 0021-9541 1097-4652 |
| language | eng |
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| source | Wiley Online Library - AutoHoldings Journals; MEDLINE |
| subjects | Central nervous system Glioblastoma - pathology Humans Hypoxia Lateral Ventricles - pathology Models, Biological Neurogenesis Stem cells Tumor Microenvironment |
| title | Glioblastoma Multiforme and Adult Neurogenesis in the Ventricular‐Subventricular Zone: A Review |
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