Outpatient desensitization in selected patients with platinum hypersensitivity reactions

Highlights • The primary risk factor for platinum hypersensitivity reactions is prior exposure. • A new classification system for hypersensitivity reactions is proposed. • A management algorithm for platinum hypersensitivity reactions is discussed. • Outpatient desensitization of patients with prior...

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Veröffentlicht in:	Gynecologic oncology 2017-06, Vol.145 (3), p.603-610
Hauptverfasser:	O'Malley, David M, Vetter, Monica Hagan, Cohn, David E, Khan, Ambar, Hays, John L
Format:	Artikel
Sprache:	eng
Schlagworte:	Algorithms Ambulatory Care Carboplatin Carboplatin - adverse effects Cisplatin - adverse effects Desensitization Desensitization, Immunologic - methods Drug Hypersensitivity - etiology Drug Hypersensitivity - immunology Drug Hypersensitivity - therapy Female Genital Neoplasms, Female - drug therapy Hematology, Oncology and Palliative Medicine Humans Hypersensitivity reactions Obstetrics and Gynecology
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Beschreibung
Zusammenfassung:	Highlights • The primary risk factor for platinum hypersensitivity reactions is prior exposure. • A new classification system for hypersensitivity reactions is proposed. • A management algorithm for platinum hypersensitivity reactions is discussed. • Outpatient desensitization of patients with prior reactions is feasible.
ISSN:	0090-8258 1095-6859
DOI:	10.1016/j.ygyno.2017.03.015