Prepulse inhibition during withdrawal from an escalating dosage schedule of amphetamine

Psychomotor stimulants can induce psychotic states in humans that closely resemble those observed in patients with idiopathic schizophrenia. Attentional and sensorimotor gating impairments are observed in schizophrenic patients using the latent inhibition (LI) and prepulse inhibition (PPI) behaviora...

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Veröffentlicht in:	Psychopharmacology 2003-09, Vol.169 (3-4), p.340-353
Hauptverfasser:	Russig, Holger, Murphy, Carol A, Feldon, Joram
Format:	Artikel
Sprache:	eng
Schlagworte:	Acoustic Stimulation Analysis of Variance Animals Avoidance Learning - drug effects Behavior, Animal - drug effects Central Nervous System Stimulants - pharmacology Conditioning, Classical - drug effects Cues Dextroamphetamine - pharmacology Dose-Response Relationship, Drug Drug Administration Schedule Inhibition (Psychology) Male Motor Activity - drug effects Rats Rats, Wistar Reflex, Startle - drug effects Stereotyped Behavior - drug effects Substance Withdrawal Syndrome - psychology Time Factors
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