Tenofovir-Related Nephrotoxicity in Human Immunodeficiency Virus-Infected Patients: Three Cases of Renal Failure, Fanconi Syndrome, and Nephrogenic Diabetes Insipidus

We report 3 cases of renal toxicity associated with use of the antiviral agent tenofovir. Renal failure, proximal tubular dysfunction, and nephrogenic diabetes insipidus were observed, and, in 2 cases, renal biopsy revealed severe tubular necrosis with characteristic nuclear changes. Patients receiv...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Clinical infectious diseases 2003-04, Vol.36 (8), p.1070-1073
Hauptverfasser:	Karras, Alexandre, Lafaurie, Matthieu, Furco, André, Bourgarit, Anne, Droz, Dominique, Sereni, Daniel, Legendre, Christophe, Martinez, Frank, Molina, Jean-Michel
Format:	Artikel
Sprache:	eng
Schlagworte:	Acidosis Acidosis - etiology Adenine - adverse effects Adenine - analogs & derivatives Adult Anti-HIV Agents - adverse effects Antivirals Biological and medical sciences Biopsies Creatinine - blood Diabetes Insipidus, Nephrogenic - etiology Diabetes Insipidus, Nephrogenic - pathology Drug Monitoring Drug toxicity and drugs side effects treatment Epithelial cells Fanconi syndrome Fanconi Syndrome - etiology Fanconi Syndrome - pathology Glycosuria - etiology HIV Infections - drug therapy HIV/AIDS Human viral diseases Humans Infectious diseases Kidney failure Medical sciences Middle Aged Necrosis Nephrotoxicity Nucleotides Organophosphonates Organophosphorus Compounds - adverse effects Pharmacology. Drug treatments Proteinuria Proteinuria - etiology Renal Insufficiency - etiology Renal Insufficiency - pathology Tenofovir Toxicity: urogenital system Viral diseases Viral diseases of the lymphoid tissue and the blood. Aids
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!