The Resurgence of Xenotransplantation

There has been an upsurge of interest in xenotransplantation in recent years. This resurgence can attributed to a combination of factors. First, there has been a dramatic improvement in efficacy in several preclinical models, with maximum xenograft survival times increasing to 950 days for islets, 9...

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Veröffentlicht in:	American journal of transplantation 2017-10, Vol.17 (10), p.2531-2536
Hauptverfasser:	Cowan, P. J., Tector, A. J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animal models animal models: nonhuman primate Animals basic (laboratory) research/science Clinical trials cloning Clustered Regularly Interspaced Short Palindromic Repeats Genome editing Genomes Graft rejection Graft Survival Heart Humans Immunosuppression Swine translational research/science Transplantation Transplantation, Heterologous - adverse effects Transplantation, Heterologous - statistics & numerical data xenoantibody xenoantigen Xenografts Xenotransplantation
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