Interferon-γ production by tubulointerstitial human CD56bright natural killer cells contributes to renal fibrosis and chronic kidney disease progression

Natural killer (NK) cells are a population of lymphoid cells that play a significant role in mediating innate immune responses. Studies in mice suggest a pathological role for NK cells in models of kidney disease. In this study, we characterized the NK cell subsets present in native kidneys of patie...

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Veröffentlicht in:	Kidney international 2017-07, Vol.92 (1), p.79-88
Hauptverfasser:	Law, Becker M.P., Wilkinson, Ray, Wang, Xiangju, Kildey, Katrina, Lindner, Mae, Rist, Melissa J., Beagley, Kenneth, Healy, Helen, Kassianos, Andrew J.
Format:	Artikel
Sprache:	eng
Schlagworte:	chronic kidney disease human natural killer cells interferon-γ interstitial fibrosis tubulointerstitium
Online-Zugang:	Volltext
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