Emulsion of Chloramphenicol: an Overwhelming Approach for Ocular Delivery

Ophthalmic formulations of chloramphenicol have poor bioavailability of chloramphenicol in the ocular cavity. The present study aimed at exploring the impact of different oil mixtures in the form of emulsion on the permeability of chloramphenicol after ocular application. Selection of oil mixture an...

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Veröffentlicht in:	Folia Medica 2017-03, Vol.59 (1), p.23-30
Hauptverfasser:	Ashara, Kalpesh C, Shah, Ketan V
Format:	Artikel
Sprache:	eng
Schlagworte:	Administration, Ophthalmic Animals Anti-Bacterial Agents - administration & dosage Anti-Bacterial Agents - pharmacokinetics Biological Availability biphasic system chloramphenicol Chloramphenicol - administration & dosage Chloramphenicol - pharmacokinetics constrained simplexcentroid design emulsion Emulsions - administration & dosage Emulsions - chemistry Emulsions - pharmacokinetics Eye - metabolism Glycerides Goats ocular accumulation Olive Oil Ophthalmic Solutions Plant Oils Polyethylene Glycols - administration & dosage Polyethylene Glycols - chemistry Polyethylene Glycols - pharmacokinetics Terpenes
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