Retinal Photoreceptor Functions Are Compromised in Patients With Resistance to Thyroid Hormone Syndrome (RTHβ)

Context:In animal models, disruption of thyroid hormone (TH) receptor-β (TRβ) reduces the long/medium wavelength (L/M) and increases the short-wavelength (S) cones. Retinal photoreceptor (RP) functions are unknown in patients with resistance to TH syndrome (RTHβ) with dominant-negative TRβ mutations...

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Veröffentlicht in:	The journal of clinical endocrinology and metabolism 2017-07, Vol.102 (7), p.2620-2627
Hauptverfasser:	Campi, Irene, Cammarata, Gabriella, Bianchi Marzoli, Stefania, Beck-Peccoz, Paolo, Santarsiero, Diletta, Dazzi, Davide, Bottari de Castello, Alessandra, Taroni, Elena Giuliana, Viola, Francesco, Mian, Caterina, Watutantrige-Fernando, Sara, Pelusi, Carla, Muzza, Marina, Maffini, Maria Antonia, Persani, Luca
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Animal models Case-Control Studies Color Color matching Color sensitivity Color vision Color Vision - physiology Color Vision Defects - diagnosis Cones Electrophysiology Electroretinograms Electroretinography - methods Female Helper cells Humans Italy Lymphocytes T Male Middle Aged Optical Coherence Tomography Photoreceptor Cells, Vertebrate - pathology Photoreceptors Prenatal experience Prenatal exposure Reference Values Retina Rods Sensitivity Sex hormones Statistics, Nonparametric Tertiary Care Centers Thyroid Function Tests Thyroid gland Thyroid hormone resistance syndrome Thyroid Hormone Resistance Syndrome - physiopathology Tomography, Optical Coherence - methods Wavelength Young Adult
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