Retinoic Acid Receptor β: A Potential Therapeutic Target in Retinoic Acid Treatment of Endometrial Cancer

Several studies have reported that retinoic acid (RA) might be used to treat malignancies. The effects of RA are mediated by the RA receptor (RAR), and RARα/RARβ especially acts as a tumor suppressor. However, little is known about its role in human endometrial cancer. In this study, we examined the...

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Veröffentlicht in:	International journal of gynecological cancer 2017-05, Vol.27 (4), p.643-650
Hauptverfasser:	Tsuji, Keita, Utsunomiya, Hiroki, Miki, Yasuhiro, Hanihara, Mayu, Fue, Misaki, Takagi, Kiyoshi, Nishimoto, Mitsuo, Suzuki, Fumihiko, Yaegashi, Nobuo, Suzuki, Takashi, Ito, Kiyoshi
Format:	Artikel
Sprache:	eng
Schlagworte:	Acids Cell growth Cell Line, Tumor Cell Movement - drug effects Cell Survival - drug effects Endometrial cancer Endometrial Neoplasms - drug therapy Endometrial Neoplasms - genetics Endometrial Neoplasms - metabolism Endometrial Neoplasms - pathology Female Gene Knockdown Techniques Humans Immunohistochemistry Molecular Targeted Therapy Receptors, Retinoic Acid - biosynthesis Receptors, Retinoic Acid - deficiency Receptors, Retinoic Acid - genetics Receptors, Retinoic Acid - metabolism Retinoic Acid Receptor alpha - biosynthesis Retinoic Acid Receptor alpha - deficiency Retinoic Acid Receptor alpha - genetics Retinoic Acid Receptor alpha - metabolism Tretinoin - pharmacology
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