Two CCAAT/enhancer binding protein sites in the cytochrome P4503A1 locus: Potencial role in the glucocorticoid response

Induction of CYP3A genes by the ligand‐activated pregnane‐X‐receptor (PXR) involves the interaction of other as yet unidentified liver transcription factors. Here we show that the CYP3A1 promoter contains two active sites controlled by the CCAAT/enhancer‐binding protein α (C/EBPα), previously shown...

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Veröffentlicht in:European journal of biochemistry 2003-02, Vol.270 (3), p.556-564
Hauptverfasser: Rodrigues, Elsa, Vilarem, Marie‐José, Ribeiro, Vera, Maurel, Patrick, Lechner, Maria C.
Format: Artikel
Sprache:eng
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