Long term impact of hyperleukocytosis in newly diagnosed acute myeloid leukemia patients undergoing allogeneic stem cell transplantation: An analysis from the acute leukemia working party of the EBMT

Up to 20% of acute myeloid leukemia (AML) patients present initially with hyperleukocytosis, placing them at increased risk for early mortality during induction. Yet, it is unknown whether hyperleukocytosis still retains prognostic value for AML patients undergoing hematopoietic stem cell transplant...

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Veröffentlicht in:	American journal of hematology 2017-07, Vol.92 (7), p.653-659
Hauptverfasser:	Canaani, Jonathan, Labopin, Myriam, Socié, Gerard, Nihtinen, Anne, Huynh, Anne, Cornelissen, Jan, Deconinck, Eric, Gedde‐Dahl, Tobias, Forcade, Edouard, Chevallier, Patrice, Bourhis, Jean H., Blaise, Didier, Mohty, Mohamad, Nagler, Arnon
Format:	Artikel
Sprache:	eng
Schlagworte:	Acute myeloid leukemia Adolescent Adult Aged Biomarkers, Tumor Cytogenetics Female fms-Like Tyrosine Kinase 3 - genetics Follow-Up Studies Graft vs Host Disease - epidemiology Graft vs Host Disease - etiology Hematology Hematopoietic Stem Cell Transplantation - methods Hematopoietic stem cells Humans Incidence Leukemia Leukemia, Myeloid, Acute - blood Leukemia, Myeloid, Acute - genetics Leukemia, Myeloid, Acute - mortality Leukemia, Myeloid, Acute - therapy Leukocyte Count Leukocytosis - blood Male Middle Aged Multivariate analysis Mutation Myeloid leukemia Nuclear Proteins - genetics Prognosis Proportional Hazards Models Recurrence Retrospective Studies Stem cell transplantation Stem cells Transplantation, Homologous Treatment Outcome Young Adult
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