Modulating short tryptophan- and arginine-rich peptides activity by substitution with histidine

High antimicrobial efficacy of short tryptophan-and arginine-rich peptides makes them good candidates in the fight against pathogens. Substitution of tryptophan and arginine by histidine could be used to modulate the peptides efficacy by optimizing their structures. The peptide (RRWWRWWRR), reported...

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Veröffentlicht in:Biochimica et biophysica acta. General subjects 2017-07, Vol.1861 (7), p.1844-1854
Hauptverfasser: Bacalum, Mihaela, Janosi, Lorant, Zorila, Florina, Tepes, Ana-Maria, Ionescu, Cristina, Bogdan, Elena, Hadade, Niculina, Craciun, Liviu, Grosu, Ion, Turcu, Ioan, Radu, Mihai
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Sprache:eng
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