MicroRNA-485-5p represses melanoma cell invasion and proliferation by suppressing Frizzled7

Abstract MicroRNAs (miRNAs) have emerged as critical regulators for malignant melanoma development. miR-485-5p has been suggested as a tumor-suppressive miRNA in many types of human malignancies. However, the role of miR-485-5p in melanoma remains unknown. In this study, we aimed to explore the pote...

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Veröffentlicht in:	Biomedicine & pharmacotherapy 2017-06, Vol.90, p.303-310
Hauptverfasser:	Wu, Jiawen, Li, Jing, Ren, Jianwen, Zhang, Dingwei
Format:	Artikel
Sprache:	eng
Schlagworte:	3' Untranslated Regions - genetics Apoptosis - genetics Cell Line, Tumor Cell Movement - genetics Cell Proliferation - genetics Frizzled Receptors - genetics FZD7 Gene Expression Regulation, Neoplastic - genetics Humans Internal Medicine Medical Education Melanoma Melanoma - genetics Melanoma - pathology MicroRNAs - genetics MiR-485-5p Neoplasm Invasiveness - genetics Neoplasm Invasiveness - pathology Signal Transduction - genetics Wnt
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