The LargPAD Trial: Phase IIA evaluation of l -arginine infusion in patients with peripheral arterial disease

Abstract Objective Endothelial function is improved by l- arginine ( l- arg) supplementation in preclinical and clinical studies of mildly diseased vasculature; however, endothelial function and responsiveness to l- arg in severely diseased arteries is not known. Our objective was to evaluate the ac...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Journal of vascular surgery 2017-07, Vol.66 (1), p.187-194
Hauptverfasser:	Kashyap, Vikram S., MD, Lakin, Ryan O., MD, Campos, Patricia, BSE, Allemang, Matthew, MD, Kim, Ann, MD, Sarac, Timur P., MD, Hausladen, Alfred, PhD, Stamler, Jonathan S., MD
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetylcholine - administration & dosage Angiography Arginine - administration & dosage Arginine - adverse effects Arginine - blood Chronic Disease Dose-Response Relationship, Drug Endothelium, Vascular - drug effects Endothelium, Vascular - physiopathology Female Femoral Artery - diagnostic imaging Femoral Artery - drug effects Femoral Artery - physiopathology Humans Infusions, Intra-Arterial Ischemia - diagnostic imaging Ischemia - drug therapy Ischemia - physiopathology Lower Extremity - blood supply Male Middle Aged Nitrogen Oxides - blood Nitroglycerin - administration & dosage Ohio Ornithine - blood Peripheral Arterial Disease - diagnostic imaging Peripheral Arterial Disease - drug therapy Peripheral Arterial Disease - physiopathology Plaque, Atherosclerotic Prospective Studies Regional Blood Flow Surgery Time Factors Treatment Outcome Ultrasonography, Doppler, Duplex Ultrasonography, Interventional Vasodilation - drug effects Vasodilator Agents - administration & dosage Vasodilator Agents - adverse effects Vasodilator Agents - blood
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!