Cancer stem cells with increased metastatic potential as a therapeutic target for esophageal cancer

Abstract Esophageal cancers (EC) are highly aggressive tumors, commonly presented in a locally advanced stage with a poor prognosis and survival. Up to 50% of the patients are eligible for treated with curative intent and receive the standard treatment with neoadjuvant chemoradiotherapy (nCRT) and s...

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Veröffentlicht in:	Seminars in cancer biology 2017-06, Vol.44, p.60-66
Hauptverfasser:	Wang, D, Plukker, J.Th.M, Coppes, R.P
Format:	Artikel
Sprache:	eng
Schlagworte:	Autophagy - drug effects Cancer stem cells Cell Hypoxia - drug effects Epithelial-Mesenchymal Transition - drug effects Esophageal Neoplasms - drug therapy Esophageal Neoplasms - genetics Esophageal Neoplasms - pathology Hematology, Oncology and Palliative Medicine Humans Metastases and esophageal cancer Neoadjuvant Therapy - methods Neoplasm Metastasis Neoplastic Stem Cells - drug effects
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