Identification of an Autoinhibitory Domain of p21-activated Protein Kinase 5

The p21-activated protein kinases (Paks) are serine/threonine protein kinases activated by binding to Rho family small GTPases, Rac and Cdc42. Recently, Pak family members have been subdivided into two groups, I and II. Group II Paks, including Pak4, Pak5, and Pak6, does not contain the highly conse...

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Veröffentlicht in:	The Journal of biological chemistry 2003-09, Vol.278 (36), p.33621-33624
Hauptverfasser:	Ching, Yick-Pang, Leong, Veronica Y.L., Wong, Chi-Ming, Kung, Hsiang-Fu
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence cdc42 GTP-Binding Protein - metabolism Cell Line Gene Deletion Glutathione Transferase - metabolism Guanosine Triphosphate - metabolism Histidine - chemistry Humans Leucine - chemistry Molecular Sequence Data Mutation p21-Activated Kinases Phosphorylation Plasmids - metabolism Protein Binding Protein Structure, Tertiary Protein-Serine-Threonine Kinases - metabolism Recombinant Fusion Proteins - metabolism Sequence Homology, Amino Acid Transfection Tyrosine - chemistry
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