Impact of Allogeneic Hematopoietic Stem Cell Transplantation on the HIV Reservoir and Immune Response in 3 HIV-Infected Individuals

Allogeneic hematopoietic stem cell transplantation (HSCT) can lead to significant changes to the HIV reservoir and HIV immune responses, indicating that further characterization of HIV-infected patients undergoing HSCT is warranted. We studied 3 patients who underwent HSCT after either reduced inten...

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Veröffentlicht in:	Journal of acquired immune deficiency syndromes (1999) 2017-07, Vol.75 (3), p.328-337
Hauptverfasser:	Koelsch, Kersten K, Rasmussen, Thomas A, Hey-Nguyen, William J, Pearson, Chester, Xu, Yin, Bailey, Michelle, Marks, Katherine H, Sasson, Sarah C, Taylor, Mark S, Tantau, Robyn, Obeid, Solange, Milner, Brad, Morrissey, Orla, Pinto, Angie N, Suzuki, Kazuo, Busch, Michael P, Keating, Sheila M, Kaiser, Philipp, Yukl, Steven, Wong, Joseph K, Hiener, Bonnie M, Palmer, Sarah, Zaunders, John, Post, Jeffrey J, Chan, Derek J, Avery, Sharon, Milliken, Sam T, Kelleher, Anthony D, Lewin, Sharon R, Cooper, David A
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult AIDS/HIV Antibodies Antigens Antiretroviral agents Antiretroviral therapy Antiretroviral Therapy, Highly Active CD4 antigen CD4-Positive T-Lymphocytes - immunology Conditioning Deoxyribonucleic acid DNA DNA, Viral - blood Hematopoietic Stem Cell Transplantation HIV HIV Infections - immunology HIV Infections - therapy HIV Infections - virology Human immunodeficiency virus Humans Immune response Immune system Impact analysis Leukocytes (mononuclear) Lymph Lymph nodes Lymphocytes Lymphocytes T Male Middle Aged Patients Peripheral blood mononuclear cells Remission Remission Induction Ribonucleic acid RNA RNA, Viral - blood Stem cell transplantation Stem cells Transplantation Transplantation Conditioning Transplants & implants Treatment Outcome Viral Load - immunology Young Adult
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