Molecular Imprinting on Inorganic Nanozymes for Hundred-fold Enzyme Specificity

Enzyme-mimicking nanomaterials (nanozymes) are more cost-effective and robust than protein enzymes, but they lack specificity. Herein, molecularly imprinted polymers were grown on Fe3O4 nanozymes with peroxidase-like activity to create substrate binding pockets. Electron microscopy confirmed a shell...

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Veröffentlicht in:	Journal of the American Chemical Society 2017-04, Vol.139 (15), p.5412-5419
Hauptverfasser:	Zhang, Zijie, Zhang, Xiaohan, Liu, Biwu, Liu, Juewen
Format:	Artikel
Sprache:	eng
Schlagworte:	Ferric Compounds - chemistry Ferric Compounds - metabolism Molecular Imprinting Nanostructures - chemistry Oxidoreductases - chemistry Oxidoreductases - metabolism Particle Size Peroxidase - chemistry Peroxidase - metabolism Substrate Specificity Surface Properties
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