Role of autophagy in advanced atherosclerosis

Atherosclerosis (AS) remains the leading cause for global cardiovascular disease morbidity and mortality, and a major cause of cardiopathy, myocardial infarction and peripheral vascular diseases. Macrophages serve a critical role in atherosclerotic plaque stabilization and rupture, and the selective...

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Veröffentlicht in:	Molecular medicine reports 2017-05, Vol.15 (5), p.2903-2908
Hauptverfasser:	Zhu, Yu-Ning, Fan, Wen-Jing, Zhang, Chi, Guo, Fang, Li, Wei, Wang, Yu-Fei, Jiang, Zhi-Sheng, Qu, Shun-Lin
Format:	Artikel
Sprache:	eng
Schlagworte:	Apoptosis Arteriosclerosis Ataxia Telangiectasia Mutated Proteins - metabolism Atherosclerosis Atherosclerosis - metabolism Atherosclerosis - pathology Autophagy Autophagy (Cytology) Cardiovascular disease Cardiovascular diseases Cardiovascular system Care and treatment Cell survival Development and progression Health aspects Homeostasis Humans Inflammation Kinases Lipids Lysosomal-Associated Membrane Protein 2 - metabolism Macrophages Macrophages - immunology Macrophages - metabolism Mammals Metabolism molecular mechanism Morbidity Myocardial infarction Organelles Oxidative stress Phagocytosis Protein Phosphatase 2C - metabolism Proteins Rodents Severity of Illness Index Stem cells TOR Serine-Threonine Kinases - metabolism treatment vascular Vascular diseases Yeast
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