Study of N‐vinylpyrrolidone‐N‐vinylformamide copolymers labelled with indium‐113m

The procedure of the directed synthesis of N‐vinylpyrrolidone‐N‐vinylformamide (VP‐VFA) copolymers with grafted iminodiacetate (IDA) chelating units is presented. The methods for labelling resulting conjugates with indium‐113m were developed. The metal‐copolymer conjugates were characterized by diff...

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Veröffentlicht in:	Journal of labelled compounds & radiopharmaceuticals 2017-05, Vol.60 (6), p.302-311
Hauptverfasser:	Gorshkov, N.I., Miroslavov, А.Е., Аlekseev, I.Е., Lumpov, А.А., Мurko, А.Y., Gavrilova, I.I., Saprykina, N.N., Bezrukova, М.А., Kipper, А.I., Krasikov, V.D., Suglobov, D.N., Tyupina, M.Y., Panarin, Е.F.
Format:	Artikel
Sprache:	eng
Schlagworte:	bioconjugates Chelation Chemical synthesis Conjugates Copolymers Formamides - chemistry Graft copolymers High performance liquid chromatography Histidine Histidine - chemistry Indium Indium Radioisotopes - chemistry indium‐113m Labeling labelling Light scattering NMR Nuclear magnetic resonance N‐vinylpyrrolidone‐N‐vinylformamide copolymer pH effects Polymers - chemistry Pyrrolidinones - chemistry radiochemical synthesis Radiochemistry site specific radiopharmaceuticals Vinylpyrrolidone Viscometry
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