Agreement between Automated and Manual Quantification of Corneal Nerve Fibre Length: Implications for Diabetic Neuropathy Research

Abstract Aims Quantification of corneal nerve fiber length (CNFL) by in vivo corneal confocal microscopy represents a promising diabetic neuropathy biomarker, but applicability is limited by resource-intensive image analysis. We aimed to evaluate, in cross-sectional analysis of non-diabetic controls...

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Veröffentlicht in:	Journal of diabetes and its complications 2017-06, Vol.31 (6), p.1066-1073
Hauptverfasser:	Scarr, Daniel, Lovblom, Leif E, Ostrovski, Ilia, Kelly, Dylan, Wu, Tong, Farooqi, Mohammed A, Halpern, Elise M, Ngo, Mylan, Ng, Eduardo, Orszag, Andrej, Bril, Vera, Perkins, Bruce A
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Automation Biomarkers Biopsy Case-Control Studies Clinical medicine Cornea Cornea - innervation Cornea - pathology Corneal confocal microscopy Corneal nerve fiber length Cross-Sectional Studies Diabetes Diabetes Mellitus, Type 1 - complications Diabetes Mellitus, Type 1 - diagnosis Diabetes Mellitus, Type 1 - pathology Diabetes Mellitus, Type 2 - complications Diabetes Mellitus, Type 2 - diagnosis Diabetes Mellitus, Type 2 - pathology Diabetic Neuropathies - diagnosis Diabetic Neuropathies - pathology Diabetic neuropathy Diabetic Retinopathy - diagnosis Diabetic Retinopathy - pathology Diagnostic Techniques, Ophthalmological Endocrinology & Metabolism Female Humans Image Processing, Computer-Assisted - methods Male Measurement Microscopy Microscopy, Confocal Middle Aged Morphology Nerve Fibers - pathology Neuropathy Neurosciences Pattern Recognition, Automated - methods Peripheral neuropathy Physical Examination - methods
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