Modulating Oxidative Stress Relieves Stress-Induced Behavioral and Cognitive Impairments in Rats

Background:Persistent psychological stress often leads to anxiety disorders and depression. Benzodiazepines and selective serotonin reuptake inhibitors are popular treatment options but have limited efficacy, supporting the need for alternative treatment. Based on our recent preclinical work suggest...

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Veröffentlicht in:	The international journal of neuropsychopharmacology 2017-07, Vol.20 (7), p.550-561
Hauptverfasser:	Solanki, Naimesh, Salvi, Ankita, Patki, Gaurav, Salim, Samina
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antioxidants - pharmacology Antioxidants - therapeutic use Brain - drug effects Brain - metabolism Cell Line, Transformed Cognition Disorders - drug therapy Cognition Disorders - etiology Corticosterone - metabolism Disease Models, Animal Hippocampus - cytology Lactoylglutathione Lyase - metabolism Male Maze Learning - drug effects Mice Mood Disorders - drug therapy Mood Disorders - etiology Neurons - drug effects Neurons - metabolism Oxidative Stress - drug effects Oxidative Stress - physiology Plant Extracts - pharmacology Rats Rats, Sprague-Dawley Stress, Psychological - complications Vitis - chemistry
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