30 YEARS OF THE MINERALOCORTICOID RECEPTOR: Mineralocorticoid receptor and NaCl transport mechanisms in the renal distal nephron

A key role of aldosterone and mineralocorticoid receptor is to regulate fluid volume and K+ homeostasis in the body by acting on the renal distal nephron. Global responses of the kidney to elevated aldosterone levels are determined by the coordinate action of different constituent tubule cells, incl...

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Veröffentlicht in:	Journal of endocrinology 2017-07, Vol.234 (1), p.T35-T47
1. Verfasser:	Shibata, Shigeru
Format:	Artikel
Sprache:	eng
Schlagworte:	Adrenal glands Aldosterone Aldosterone - metabolism Angiotensin Angiotensin II Animals Cullin Gene Expression Regulation - physiology Homeostasis Kidneys Mutation Nephrons - physiology Phosphorylation Potassium Reabsorption Receptors, Mineralocorticoid - metabolism Secretion Sodium Sodium chloride Sodium Chloride - metabolism Thematic Review Ubiquitin Ubiquitin-protein ligase
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