Do-not-resuscitate orders and early mortality in hip fracture patients
factors affecting mortality after hip fracture surgery have been studied extensively. It has been suggested that do-not-resuscitate (DNR) orders are associated with higher mortality in surgical patients due to less aggressive treatment. However, the effect of DNR orders on mortality in hip fracture...
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Veröffentlicht in: | Age and ageing 2017-11, Vol.46 (6), p.946-951 |
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description | factors affecting mortality after hip fracture surgery have been studied extensively. It has been suggested that do-not-resuscitate (DNR) orders are associated with higher mortality in surgical patients due to less aggressive treatment. However, the effect of DNR orders on mortality in hip fracture patients is unknown. The objective of this study was to investigate the effect of DNR orders on early mortality after hip fracture surgery.
all patients undergoing hip fracture surgery between 2004 and 2015 were included in this retrospective study. Patient characteristics such as age, comorbidities and fracture type were collected, as were resuscitation preferences. Multivariable logistic regression analysis was performed to identify independent risk factors for early mortality.
a total of 1,803 patients were analysed, of which 823 (45.6%) had DNR orders. DNR patients were older, more often female, had lower haemoglobin levels and more comorbidities when compared with non-DNR patients. The unadjusted effect of DNR orders on mortality was high (OR: 2.39; P < 0.001). Multivariable analysis demonstrated that increased age, male gender, higher American Society of Anesthesiologists score, low admission haemoglobin, living in an institution, high Charlson Comorbidity Index and delay to surgery were associated with increased early mortality after hip fracture surgery. There was no independent effect of DNR orders on mortality after adjustment for these variables (P = 0.735).
DNR patients have higher mortality rates due to poor health status. Resuscitation preferences on their own are not associated with early mortality after hip fracture surgery. |
doi_str_mv | 10.1093/ageing/afx027 |
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all patients undergoing hip fracture surgery between 2004 and 2015 were included in this retrospective study. Patient characteristics such as age, comorbidities and fracture type were collected, as were resuscitation preferences. Multivariable logistic regression analysis was performed to identify independent risk factors for early mortality.
a total of 1,803 patients were analysed, of which 823 (45.6%) had DNR orders. DNR patients were older, more often female, had lower haemoglobin levels and more comorbidities when compared with non-DNR patients. The unadjusted effect of DNR orders on mortality was high (OR: 2.39; P < 0.001). Multivariable analysis demonstrated that increased age, male gender, higher American Society of Anesthesiologists score, low admission haemoglobin, living in an institution, high Charlson Comorbidity Index and delay to surgery were associated with increased early mortality after hip fracture surgery. There was no independent effect of DNR orders on mortality after adjustment for these variables (P = 0.735).
DNR patients have higher mortality rates due to poor health status. Resuscitation preferences on their own are not associated with early mortality after hip fracture surgery.</description><identifier>ISSN: 0002-0729</identifier><identifier>EISSN: 1468-2834</identifier><identifier>DOI: 10.1093/ageing/afx027</identifier><identifier>PMID: 28338851</identifier><language>eng</language><publisher>England: Oxford University Press</publisher><subject>Age Factors ; Aged ; Aged, 80 and over ; Aging ; Care and treatment ; Chi-Square Distribution ; Comorbidity ; Elderly ; Female ; Fracture Fixation - adverse effects ; Fracture Fixation - mortality ; Fractures ; Geriatric Assessment ; Health aspects ; Hip fractures ; Hip Fractures - diagnosis ; Hip Fractures - mortality ; Hip Fractures - surgery ; Hip joint ; Hospital Mortality ; Humans ; Logistic Models ; Male ; Middle Aged ; Mortality ; Multivariate Analysis ; Odds Ratio ; Resuscitation Orders ; Retrospective Studies ; Risk Factors ; Time Factors ; Treatment Outcome</subject><ispartof>Age and ageing, 2017-11, Vol.46 (6), p.946-951</ispartof><rights>The Author 2017. Published by Oxford University Press on behalf of the British Geriatrics Society.All rights reserved. For Permissions, please email: journals.permissions@oup.com</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c370t-7d1fb24051e6fe8ba2d0e854c8e457083bebd757d00246be9dfce25982285b93</citedby><cites>FETCH-LOGICAL-c370t-7d1fb24051e6fe8ba2d0e854c8e457083bebd757d00246be9dfce25982285b93</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27923,27924</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/28338851$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Simons, Anouk E</creatorcontrib><creatorcontrib>Karres, Julian</creatorcontrib><creatorcontrib>Nijland, Leontien M G</creatorcontrib><creatorcontrib>Ultee, Jan M</creatorcontrib><creatorcontrib>Kerkhoffs, Gino M M J</creatorcontrib><creatorcontrib>Vrouenraets, Bart C</creatorcontrib><title>Do-not-resuscitate orders and early mortality in hip fracture patients</title><title>Age and ageing</title><addtitle>Age Ageing</addtitle><description>factors affecting mortality after hip fracture surgery have been studied extensively. It has been suggested that do-not-resuscitate (DNR) orders are associated with higher mortality in surgical patients due to less aggressive treatment. However, the effect of DNR orders on mortality in hip fracture patients is unknown. The objective of this study was to investigate the effect of DNR orders on early mortality after hip fracture surgery.
all patients undergoing hip fracture surgery between 2004 and 2015 were included in this retrospective study. Patient characteristics such as age, comorbidities and fracture type were collected, as were resuscitation preferences. Multivariable logistic regression analysis was performed to identify independent risk factors for early mortality.
a total of 1,803 patients were analysed, of which 823 (45.6%) had DNR orders. DNR patients were older, more often female, had lower haemoglobin levels and more comorbidities when compared with non-DNR patients. The unadjusted effect of DNR orders on mortality was high (OR: 2.39; P < 0.001). Multivariable analysis demonstrated that increased age, male gender, higher American Society of Anesthesiologists score, low admission haemoglobin, living in an institution, high Charlson Comorbidity Index and delay to surgery were associated with increased early mortality after hip fracture surgery. There was no independent effect of DNR orders on mortality after adjustment for these variables (P = 0.735).
DNR patients have higher mortality rates due to poor health status. Resuscitation preferences on their own are not associated with early mortality after hip fracture surgery.</description><subject>Age Factors</subject><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Aging</subject><subject>Care and treatment</subject><subject>Chi-Square Distribution</subject><subject>Comorbidity</subject><subject>Elderly</subject><subject>Female</subject><subject>Fracture Fixation - adverse effects</subject><subject>Fracture Fixation - mortality</subject><subject>Fractures</subject><subject>Geriatric Assessment</subject><subject>Health aspects</subject><subject>Hip fractures</subject><subject>Hip Fractures - diagnosis</subject><subject>Hip Fractures - mortality</subject><subject>Hip Fractures - surgery</subject><subject>Hip joint</subject><subject>Hospital Mortality</subject><subject>Humans</subject><subject>Logistic Models</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Mortality</subject><subject>Multivariate Analysis</subject><subject>Odds Ratio</subject><subject>Resuscitation Orders</subject><subject>Retrospective Studies</subject><subject>Risk Factors</subject><subject>Time Factors</subject><subject>Treatment Outcome</subject><issn>0002-0729</issn><issn>1468-2834</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2017</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpFkEFLwzAUgIMobk6PXqVHL3VJmjTpcUynwmCX3UOavtZI28wkhe3fW-nU0-PxPh4fH0L3BD8RXGRL3YDtm6Wuj5iKCzQnLJcplRm7RHOMMU2xoMUM3YTwOa6EE3qNZuM9k5KTOdo8u7R3MfUQhmBs1BES5yvwIdF9lYD27SnpnI-6tfGU2D75sIek9trEwUNy0NFCH8Mtuqp1G-DuPBdov3nZr9_S7e71fb3apiYTOKaiInVJGeYE8hpkqWmFQXJmJDAusMxKKCvBRTWKs7yEoqoNUF5ISiUvi2yBHqe3B---BghRdTYYaFvdgxuCIlISmjNW0BFNJ7TRLSjbG9dHOEbj2hYaUKPVeqdWnBRUCpbl_7zxLgQPtTp422l_UgSrn9JqKq2m0iP_cFYZyg6qP_o3bfYNk4l67g</recordid><startdate>20171101</startdate><enddate>20171101</enddate><creator>Simons, Anouk E</creator><creator>Karres, Julian</creator><creator>Nijland, Leontien M G</creator><creator>Ultee, Jan M</creator><creator>Kerkhoffs, Gino M M J</creator><creator>Vrouenraets, Bart C</creator><general>Oxford University Press</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20171101</creationdate><title>Do-not-resuscitate orders and early mortality in hip fracture patients</title><author>Simons, Anouk E ; Karres, Julian ; Nijland, Leontien M G ; Ultee, Jan M ; Kerkhoffs, Gino M M J ; Vrouenraets, Bart C</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c370t-7d1fb24051e6fe8ba2d0e854c8e457083bebd757d00246be9dfce25982285b93</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2017</creationdate><topic>Age Factors</topic><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>Aging</topic><topic>Care and treatment</topic><topic>Chi-Square Distribution</topic><topic>Comorbidity</topic><topic>Elderly</topic><topic>Female</topic><topic>Fracture Fixation - adverse effects</topic><topic>Fracture Fixation - mortality</topic><topic>Fractures</topic><topic>Geriatric Assessment</topic><topic>Health aspects</topic><topic>Hip fractures</topic><topic>Hip Fractures - diagnosis</topic><topic>Hip Fractures - mortality</topic><topic>Hip Fractures - surgery</topic><topic>Hip joint</topic><topic>Hospital Mortality</topic><topic>Humans</topic><topic>Logistic Models</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Mortality</topic><topic>Multivariate Analysis</topic><topic>Odds Ratio</topic><topic>Resuscitation Orders</topic><topic>Retrospective Studies</topic><topic>Risk Factors</topic><topic>Time Factors</topic><topic>Treatment Outcome</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Simons, Anouk E</creatorcontrib><creatorcontrib>Karres, Julian</creatorcontrib><creatorcontrib>Nijland, Leontien M G</creatorcontrib><creatorcontrib>Ultee, Jan M</creatorcontrib><creatorcontrib>Kerkhoffs, Gino M M J</creatorcontrib><creatorcontrib>Vrouenraets, Bart C</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Age and ageing</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Simons, Anouk E</au><au>Karres, Julian</au><au>Nijland, Leontien M G</au><au>Ultee, Jan M</au><au>Kerkhoffs, Gino M M J</au><au>Vrouenraets, Bart C</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Do-not-resuscitate orders and early mortality in hip fracture patients</atitle><jtitle>Age and ageing</jtitle><addtitle>Age Ageing</addtitle><date>2017-11-01</date><risdate>2017</risdate><volume>46</volume><issue>6</issue><spage>946</spage><epage>951</epage><pages>946-951</pages><issn>0002-0729</issn><eissn>1468-2834</eissn><abstract>factors affecting mortality after hip fracture surgery have been studied extensively. It has been suggested that do-not-resuscitate (DNR) orders are associated with higher mortality in surgical patients due to less aggressive treatment. However, the effect of DNR orders on mortality in hip fracture patients is unknown. The objective of this study was to investigate the effect of DNR orders on early mortality after hip fracture surgery.
all patients undergoing hip fracture surgery between 2004 and 2015 were included in this retrospective study. Patient characteristics such as age, comorbidities and fracture type were collected, as were resuscitation preferences. Multivariable logistic regression analysis was performed to identify independent risk factors for early mortality.
a total of 1,803 patients were analysed, of which 823 (45.6%) had DNR orders. DNR patients were older, more often female, had lower haemoglobin levels and more comorbidities when compared with non-DNR patients. The unadjusted effect of DNR orders on mortality was high (OR: 2.39; P < 0.001). Multivariable analysis demonstrated that increased age, male gender, higher American Society of Anesthesiologists score, low admission haemoglobin, living in an institution, high Charlson Comorbidity Index and delay to surgery were associated with increased early mortality after hip fracture surgery. There was no independent effect of DNR orders on mortality after adjustment for these variables (P = 0.735).
DNR patients have higher mortality rates due to poor health status. Resuscitation preferences on their own are not associated with early mortality after hip fracture surgery.</abstract><cop>England</cop><pub>Oxford University Press</pub><pmid>28338851</pmid><doi>10.1093/ageing/afx027</doi><tpages>6</tpages><oa>free_for_read</oa></addata></record> |
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subjects | Age Factors Aged Aged, 80 and over Aging Care and treatment Chi-Square Distribution Comorbidity Elderly Female Fracture Fixation - adverse effects Fracture Fixation - mortality Fractures Geriatric Assessment Health aspects Hip fractures Hip Fractures - diagnosis Hip Fractures - mortality Hip Fractures - surgery Hip joint Hospital Mortality Humans Logistic Models Male Middle Aged Mortality Multivariate Analysis Odds Ratio Resuscitation Orders Retrospective Studies Risk Factors Time Factors Treatment Outcome |
title | Do-not-resuscitate orders and early mortality in hip fracture patients |
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