Transient Cell-intrinsic Activity Regulates the Migration and Laminar Positioning of Cortical Projection Neurons

Neocortical microcircuits are built during development and require the coordinated assembly of excitatory glutamatergic projection neurons (PNs) into functional networks. Neuronal migration is an essential step in this process. In addition to cell-intrinsic mechanisms, external cues including neurot...

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Veröffentlicht in:	Cerebral cortex (New York, N.Y. 1991) N.Y. 1991), 2017-05, Vol.27 (5), p.3052-3063
Hauptverfasser:	Hurni, Nicolas, Kolodziejczak, Marta, Tomasello, Ugo, Badia, Joan, Jacobshagen, Moritz, Prados, Julien, Dayer, Alexandre
Format:	Artikel
Sprache:	eng
Schlagworte:	Age Factors Animals Animals, Newborn Body Patterning Calcium - metabolism Cell Movement - genetics Cell Movement - physiology Cerebral Cortex - cytology Cerebral Cortex - metabolism Clozapine - analogs & derivatives Clozapine - pharmacology Electroporation Embryo, Mammalian Female Green Fluorescent Proteins - genetics Green Fluorescent Proteins - metabolism Homeodomain Proteins - metabolism In Vitro Techniques Mice Nerve Net - physiology Nerve Tissue Proteins - metabolism Neurons - classification Neurons - cytology Neurons - physiology Nuclear Proteins - metabolism POU Domain Factors - metabolism Pregnancy Receptor, Muscarinic M3 - genetics Receptor, Muscarinic M3 - metabolism Receptors, Glutamate - metabolism Repressor Proteins - metabolism RNA Splicing Factors - genetics RNA Splicing Factors - metabolism Signal Transduction T-Box Domain Proteins - metabolism Transcription Factors - genetics Transcription Factors - metabolism
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