Id-1 expression promotes cell survival through activation of NF-κB signalling pathway in prostate cancer cells

The growth-promoting effect of Id-1 (inhibitor of differentiation/DNA binding) has been demonstrated in a number of human cancers. However, the mechanisms responsible for its action are not clear. In this study, we report that in prostate cancer cells, Id-1 promotes cell survival through activation...

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Veröffentlicht in:	Oncogene 2003-07, Vol.22 (29), p.4498-4508
Hauptverfasser:	Ling, Ming-Tat, Wang, Xianghong, Ouyang, Xue-Song, Xu, Kexin, Tsao, Sai-Wah, Wong, Yong-Chuan
Format:	Artikel
Sprache:	eng
Schlagworte:	Antisense oligonucleotides Antisense therapy Apoptosis Bax protein Bcl-x protein Biological and medical sciences Caspase-3 Cell activation Cell Biology Cell proliferation Cell survival Fundamental and applied biological sciences. Psychology Human Genetics Id1 protein Intercellular adhesion molecule 1 Internal Medicine Kinases Medicine Medicine & Public Health Molecular and cellular biology NF-κB protein Nuclear transport Oncology original-paper Prostate cancer Signal transduction Tumor necrosis factor-α
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