MSK2 and MSK1 mediate the mitogen- and stress-induced phosphorylation of histoneH3 and HMG-14

Cells respond to mitogenic or stress stimuli by the rapid induction of immediate-early (IE) genes, which occurs concomitantly with the phosphorylation of histone H3 and the high-mobility-group protein HMG-14. In mammalian cells this response is mediated via ERK and p38 MAP kinase pathways, but the i...

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Veröffentlicht in:The EMBO journal 2003-06, Vol.22 (11), p.2788-2797
Hauptverfasser: Soloaga, A, Thomson, S, Wiggin, G R, Rampersaud, N, Dyson, M H, Hazzalin, CA, Mahadevan, L C, Arthur, J C
Format: Artikel
Sprache:eng
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