Placental protein 14 regulates selective B cell responses

Placental protein 14 (PP14) is a glycoprotein of the lipocalin family that acts as a negative regulator in T cell receptor-mediated activation. In this study, we investigated PP14s potential role in regulating B cell activation. While PP14-inhibited B cell proliferation, IgM secretion and the surfac...

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Veröffentlicht in:	Cellular immunology 2003-04, Vol.222 (2), p.156-163
Hauptverfasser:	Yaniv, Einat, Borovsky, Zipora, Mishan-Eisenberg, Galit, Rachmilewitz, Jacob
Format:	Artikel
Sprache:	eng
Schlagworte:	Antigens, CD19 - physiology B lymphocytes B-Lymphocytes - drug effects B-Lymphocytes - immunology CD19 Cellular activation Glycodelin Glycoproteins - pharmacology Glycoproteins - physiology Human Humans Immunoglobulin M - immunology Ionomycin - pharmacology Leukocyte Common Antigens - physiology PP14 Pregnancy Proteins - pharmacology Pregnancy Proteins - physiology Receptors, Antigen, B-Cell - physiology Tetradecanoylphorbol Acetate - pharmacology
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