Fed-batch production of recombinant [beta]-galactosidase using the universal stress promoters uspA and uspB in high cell density cultivations

A high-level production system using the universal stress promoters uspA and uspB in a fed-batch cultivation based on minimal medium was designed. In development it was shown that a standard industrial fed-batch protocol could not be used for this purpose since it failed to induce the levels of prod...

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Veröffentlicht in:	Biotechnology and bioengineering 2003-01, Vol.83 (5), p.595-603
Hauptverfasser:	Prytz, I, Sanden, A M, Nystroem, T, Farewell, A, Wahlstroem, A, Foerberg, C, Pragai, Z, Barer, M, Harwood, C, Larsson, G
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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