Keratoacanthoma en plaque/nodule: A brief report of the clinicopathological features of five cases
Keratoacanthoma (KA) is characterized by exoendophytic growth with a central keratin‐filled crater, representing the crateriform architecture. We herein report five rare cases of KA without a central keratin‐filled crater. These KA cases histopathologically showed that one or a few infundibular stru...
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Veröffentlicht in: | Journal of dermatology 2017-07, Vol.44 (7), p.803-807 |
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creator | Misago, Noriyuki Ansai, Shin‐ichi Fukumoto, Takaya Anan, Takashi Nakao, Tomokazu |
description | Keratoacanthoma (KA) is characterized by exoendophytic growth with a central keratin‐filled crater, representing the crateriform architecture. We herein report five rare cases of KA without a central keratin‐filled crater. These KA cases histopathologically showed that one or a few infundibular structures/isthmic lobules had their own open keratotic pores on the surface without a common merged keratotic plug/horn, clinically representing verrucous (keratotic) plaque/nodule, namely, “KA en plaque/nodule”. KA rarely but on occasion does show verrucous plaque (or nodular) lesions without a central keratin‐filled crater, as the notion that KA invariably shows crateriform architecture is nonsensical. |
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We herein report five rare cases of KA without a central keratin‐filled crater. These KA cases histopathologically showed that one or a few infundibular structures/isthmic lobules had their own open keratotic pores on the surface without a common merged keratotic plug/horn, clinically representing verrucous (keratotic) plaque/nodule, namely, “KA en plaque/nodule”. KA rarely but on occasion does show verrucous plaque (or nodular) lesions without a central keratin‐filled crater, as the notion that KA invariably shows crateriform architecture is nonsensical.</description><identifier>ISSN: 0385-2407</identifier><identifier>EISSN: 1346-8138</identifier><identifier>DOI: 10.1111/1346-8138.13787</identifier><identifier>PMID: 28332728</identifier><language>eng</language><publisher>England: Wiley Subscription Services, Inc</publisher><subject>Aged ; Aged, 80 and over ; Female ; Humans ; infundibular squamous cell carcinoma ; Keratin ; Keratinocytes - pathology ; Keratoacanthoma - pathology ; keratoacanthoma en plaque/nodule ; Male ; Middle Aged ; seborrheic keratosis ; Skin - cytology ; Skin - pathology ; verruca vulgaris ; verrucous carcinoma</subject><ispartof>Journal of dermatology, 2017-07, Vol.44 (7), p.803-807</ispartof><rights>2017 Japanese Dermatological Association</rights><rights>2017 Japanese Dermatological Association.</rights><rights>Copyright © 2017 Japanese Dermatological Association</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c3957-dee7149dbf9e6dd1677629ba6efa4ce9ca4969133b32cf72564c5caea187832e3</citedby><cites>FETCH-LOGICAL-c3957-dee7149dbf9e6dd1677629ba6efa4ce9ca4969133b32cf72564c5caea187832e3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1111%2F1346-8138.13787$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1111%2F1346-8138.13787$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,776,780,1411,27901,27902,45550,45551</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/28332728$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Misago, Noriyuki</creatorcontrib><creatorcontrib>Ansai, Shin‐ichi</creatorcontrib><creatorcontrib>Fukumoto, Takaya</creatorcontrib><creatorcontrib>Anan, Takashi</creatorcontrib><creatorcontrib>Nakao, Tomokazu</creatorcontrib><title>Keratoacanthoma en plaque/nodule: A brief report of the clinicopathological features of five cases</title><title>Journal of dermatology</title><addtitle>J Dermatol</addtitle><description>Keratoacanthoma (KA) is characterized by exoendophytic growth with a central keratin‐filled crater, representing the crateriform architecture. We herein report five rare cases of KA without a central keratin‐filled crater. These KA cases histopathologically showed that one or a few infundibular structures/isthmic lobules had their own open keratotic pores on the surface without a common merged keratotic plug/horn, clinically representing verrucous (keratotic) plaque/nodule, namely, “KA en plaque/nodule”. KA rarely but on occasion does show verrucous plaque (or nodular) lesions without a central keratin‐filled crater, as the notion that KA invariably shows crateriform architecture is nonsensical.</description><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Female</subject><subject>Humans</subject><subject>infundibular squamous cell carcinoma</subject><subject>Keratin</subject><subject>Keratinocytes - pathology</subject><subject>Keratoacanthoma - pathology</subject><subject>keratoacanthoma en plaque/nodule</subject><subject>Male</subject><subject>Middle Aged</subject><subject>seborrheic keratosis</subject><subject>Skin - cytology</subject><subject>Skin - pathology</subject><subject>verruca vulgaris</subject><subject>verrucous carcinoma</subject><issn>0385-2407</issn><issn>1346-8138</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2017</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkE1P3DAQhq2qqCyUc2-VpV56CRvbSWz3hviGlbjA2Zo44xLkjVM7Ae2_r7cLHHphLiONnvfV6CHkGyuPWZ4lE1VTKCbUMRNSyU9k8X75TBalUHXBq1Luk4OUnsqS65qVX8g-V0JwydWCtLcYYQpgYZgewxooDnT08GfG5RC62eMvekLb2KOjEccQJxocnR6RWt8PvQ0j5JgPv3sLnjqEaY6YtozrnzMECdNXsufAJzx63Yfk4eL8_vSqWN1dXp-erAordC2LDlGySnet09h0HWukbLhuoUEHlUVtodKNZkK0glsned1UtraAwJRUgqM4JD93vWMM-f80mXWfLHoPA4Y5GaZUWTVaapXRH_-hT2GOQ_7OMM1qWQnN60wtd5SNIaWIzoyxX0PcGFaarX6zlW22ss0__Tnx_bV3btfYvfNvvjNQ74CX3uPmoz5zc3a-K_4LJyqPQQ</recordid><startdate>201707</startdate><enddate>201707</enddate><creator>Misago, Noriyuki</creator><creator>Ansai, Shin‐ichi</creator><creator>Fukumoto, Takaya</creator><creator>Anan, Takashi</creator><creator>Nakao, Tomokazu</creator><general>Wiley Subscription Services, Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7T5</scope><scope>H94</scope><scope>K9.</scope><scope>7X8</scope></search><sort><creationdate>201707</creationdate><title>Keratoacanthoma en plaque/nodule: A brief report of the clinicopathological features of five cases</title><author>Misago, Noriyuki ; Ansai, Shin‐ichi ; Fukumoto, Takaya ; Anan, Takashi ; Nakao, Tomokazu</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3957-dee7149dbf9e6dd1677629ba6efa4ce9ca4969133b32cf72564c5caea187832e3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2017</creationdate><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>Female</topic><topic>Humans</topic><topic>infundibular squamous cell carcinoma</topic><topic>Keratin</topic><topic>Keratinocytes - pathology</topic><topic>Keratoacanthoma - pathology</topic><topic>keratoacanthoma en plaque/nodule</topic><topic>Male</topic><topic>Middle Aged</topic><topic>seborrheic keratosis</topic><topic>Skin - cytology</topic><topic>Skin - pathology</topic><topic>verruca vulgaris</topic><topic>verrucous carcinoma</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Misago, Noriyuki</creatorcontrib><creatorcontrib>Ansai, Shin‐ichi</creatorcontrib><creatorcontrib>Fukumoto, Takaya</creatorcontrib><creatorcontrib>Anan, Takashi</creatorcontrib><creatorcontrib>Nakao, Tomokazu</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Immunology Abstracts</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of dermatology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Misago, Noriyuki</au><au>Ansai, Shin‐ichi</au><au>Fukumoto, Takaya</au><au>Anan, Takashi</au><au>Nakao, Tomokazu</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Keratoacanthoma en plaque/nodule: A brief report of the clinicopathological features of five cases</atitle><jtitle>Journal of dermatology</jtitle><addtitle>J Dermatol</addtitle><date>2017-07</date><risdate>2017</risdate><volume>44</volume><issue>7</issue><spage>803</spage><epage>807</epage><pages>803-807</pages><issn>0385-2407</issn><eissn>1346-8138</eissn><abstract>Keratoacanthoma (KA) is characterized by exoendophytic growth with a central keratin‐filled crater, representing the crateriform architecture. We herein report five rare cases of KA without a central keratin‐filled crater. These KA cases histopathologically showed that one or a few infundibular structures/isthmic lobules had their own open keratotic pores on the surface without a common merged keratotic plug/horn, clinically representing verrucous (keratotic) plaque/nodule, namely, “KA en plaque/nodule”. KA rarely but on occasion does show verrucous plaque (or nodular) lesions without a central keratin‐filled crater, as the notion that KA invariably shows crateriform architecture is nonsensical.</abstract><cop>England</cop><pub>Wiley Subscription Services, Inc</pub><pmid>28332728</pmid><doi>10.1111/1346-8138.13787</doi><tpages>5</tpages></addata></record> |
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subjects | Aged Aged, 80 and over Female Humans infundibular squamous cell carcinoma Keratin Keratinocytes - pathology Keratoacanthoma - pathology keratoacanthoma en plaque/nodule Male Middle Aged seborrheic keratosis Skin - cytology Skin - pathology verruca vulgaris verrucous carcinoma |
title | Keratoacanthoma en plaque/nodule: A brief report of the clinicopathological features of five cases |
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