Benefit-risk assessment of treatments for heparin-induced thrombocytopenia

Patients with heparin-induced thrombocytopenia (HIT) are at high risk of thrombosis and should be treated with alternative anticoagulant therapy to reduce complications. The current treatment of choice is one of the approved direct thrombin inhibitors, argatroban or lepirudin. These drugs have been...

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Veröffentlicht in:	Drug safety 2003-01, Vol.26 (9), p.625-641
Hauptverfasser:	MESSMORE, Harry L, JESKE, Walter P, WEHRMACHER, William H, WALENGA, Jeanine M
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Drug toxicity and drugs side effects treatment Fibrinolytic Agents - therapeutic use Heparin - adverse effects Humans Medical sciences Pharmacology. Drug treatments Risk Assessment Thrombocytopenia - chemically induced Thrombocytopenia - drug therapy Thrombocytopenia - epidemiology Toxicity: blood
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