Role of amino acids in rheumatoid arthritis studied by metabolomics

Background Rheumatoid arthritis (RA) is a complex, chronic autoimmune disease characterized by various inflammatory symptoms, including joint swelling, joint pain, and both structural and functional joint damage. The most commonly used animal model for studying RA is mice with collagen‐induced arthr...

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Veröffentlicht in:	International journal of rheumatic diseases 2019-01, Vol.22 (1), p.38-46
Hauptverfasser:	He, Min, Harms, Amy C., Wijk, Eduard, Wang, Mei, Berger, Ruud, Koval, Slavik, Hankemeier, Thomas, Greef, Jan
Format:	Artikel
Sprache:	eng
Schlagworte:	amine metabolites Amino acids Autoimmune diseases Collagen collagen‐induced arthritis Energy expenditure Liquid chromatography Mass spectroscopy Metabolites Metabolomics mouse model Pain Plasma levels Rheumatoid arthritis Structure-function relationships systems biology
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