Profiling cellular and inflammatory changes in the airway wall of mild to moderate COPD

ABSTRACT Background and objective The objective of this study was to enumerate total cells and the number of inflammatory cell differentials in large airways (LAs) versus small airways (SAs) of mild‐moderate COPD, and against appropriate controls. Methods For LA, we used endobronchial biopsies and f...

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Veröffentlicht in:	Respirology (Carlton, Vic.) Vic.), 2017-08, Vol.22 (6), p.1125-1132
Hauptverfasser:	Eapen, Mathew S., McAlinden, Kielan, Tan, Daniel, Weston, Steven, Ward, Chris, Muller, Hans K., Walters, Eugene H., Sohal, Sukhwinder S.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Aged, 80 and over airways Bronchi - pathology CD4 antigen CD4 Lymphocyte Count CD4-Positive T-Lymphocytes CD8 antigen CD8-Positive T-Lymphocytes Chronic obstructive pulmonary disease Female Humans Inflammation Inflammation - immunology Inflammation - pathology inflammatory cells Lamina propria Leukocytes (neutrophilic) Lung - pathology lung tissue Lymphocytes T Macrophages Male Middle Aged Neutrophils Pulmonary Disease, Chronic Obstructive - immunology Pulmonary Disease, Chronic Obstructive - pathology Respiratory diseases Respiratory Mucosa - pathology Respiratory tract Respiratory tract diseases Tobacco Smoking - pathology Young Adult
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