Preparation of dual-responsive hybrid fluorescent nano probe based on graphene oxide and boronic acid/BODIPY-conjugated polymer for cell imaging

Here, we report a pH- and thermo-responsive fluorescent nanomaterial of functionalized reduced graphene oxide (rGO) with cross-linked polymer produced via catechol-boronate diol binding mechanism. When conjugated with the hydrophobic dye boron dipyrromethane (BODIPY), this material can act as a dual...

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Veröffentlicht in:	Materials Science & Engineering C 2017-02, Vol.71, p.1064-1071
Hauptverfasser:	Khoerunnisa, Kang, Eun Bi, Mazrad, Zihnil Adha Islamy, Lee, Gibaek, In, Insik, Park, Sung Young
Format:	Artikel
Sprache:	eng
Schlagworte:	Acids Boron Boron Compounds - chemistry Boron Compounds - pharmacokinetics Boron Compounds - pharmacology Boronic Acids - chemistry Boronic Acids - pharmacokinetics Boronic Acids - pharmacology Cancer Catechol Catechol chemistry Cell Line, Tumor Confocal microscopy Crosslinking Fluorescence Fluorescent Dyes - chemistry Fluorescent Dyes - pharmacokinetics Fluorescent Dyes - pharmacology Fluorescent nanomaterial Graphene Graphite - chemistry Graphite - pharmacokinetics Graphite - pharmacology Humans Hydrogen ions Hydrogen-Ion Concentration Hydrophobicity Imaging Isopropylacrylamide Lysosomes - metabolism Lysosomes - pathology Materials science Medical imaging Microscopy Nanomaterials Nanoparticles Nanoparticles - chemistry Nanostructure Neoplasms - metabolism Neoplasms - pathology Oxides pH effects pH- and thermo-responsive Physiology Polyethylene glycol Polymers Quenching Scanning microscopy
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