Chromosomal chaos silences immune surveillance

Not all cancers, and not all individuals with the same cancer type, respond equally to immunotherapy-the use of antibodies to block so-called immune checkpoints in T cells-thereby unleashing immune responses against tumor cells. This can be partially explained by nonsynonymous mutations, which can c...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Science (American Association for the Advancement of Science) 2017-01, Vol.355 (6322), p.249-250
1. Verfasser:	Zanetti, Maurizio
Format:	Artikel
Sprache:	eng
Schlagworte:	Abnormalities Aneuploidy Antibodies Cancer Chromosome aberrations Chromosomes Genetic abnormalities Immune checkpoint Immune response Immune systems Immunologic Surveillance Immunotherapy Lymphocytes Lymphocytes T Mutation Mutations Neoantigens PERSPECTIVES Surveillance T cell receptors Tumor cells Tumors
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!