HybridRanker: Integrating network topology and biomedical knowledge to prioritize cancer candidate genes

[Display omitted] •A computational method (HybridRanker) is proposed to prioritize disease genes.•HybridRanker exploits network topology and several biomedical data sources.•HybridRanker has better performance comparing to some well-known methods.•HybridRanker is applied to prioritize disease genes...

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Veröffentlicht in:Journal of biomedical informatics 2016-12, Vol.64, p.139-146
Hauptverfasser: Razaghi-Moghadam, Zahra, Abdollahi, Razieh, Goliaei, Sama, Ebrahimi, Morteza
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Sprache:eng
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