Accelerated quantification of amphetamine enantiomers in human urine using chiral liquid chromatography and on-line column-switching coupled with tandem mass spectrometry

Amphetamine (AM) is a powerful psychostimulant existing in two enantiomeric forms. Stereoselective analysis of AM in biosamples can assist clinicians and forensic experts in differentiating between abuse of illicitly synthesized racemic AM and ingestion of pharmaceutical AM formulations containing e...

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Veröffentlicht in:	Analytical and bioanalytical chemistry 2017-02, Vol.409 (5), p.1291-1300
Hauptverfasser:	Hädener, Marianne, Bruni, Pia S., Weinmann, Wolfgang, Frübis, Matthias, König, Stefan
Format:	Artikel
Sprache:	eng
Schlagworte:	Amphetamine - chemistry Amphetamine - urine Amphetamines Analytical Chemistry Attention deficit hyperactivity disorder Biochemistry Calibration Characterization and Evaluation of Materials Chemistry Chemistry and Materials Science Chromatography Chromatography, Liquid - methods Dilution Drugs Enantiomers Food Science Humans Ingestion Injection Ionization Laboratories Laboratory Medicine Liquid chromatography Mass spectrometry Mathematical analysis Measurement Methods Monitoring/Environmental Analysis Quality control Research Paper Sample preparation Scientific imaging Stereoisomerism Tandem Mass Spectrometry - methods Toxicology Urinalysis Urine
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