Evolutionary ecology of beta‐lactam gene clusters in animals

Beta‐lactam biosynthesis was thought to occur only in fungi and bacteria, but we recently reported the presence of isopenicillin N synthase in a soil‐dwelling animal, Folsomia candida. However, it has remained unclear whether this gene is part of a larger beta‐lactam biosynthesis pathway and how wid...

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Veröffentlicht in:	Molecular ecology 2017-06, Vol.26 (12), p.3217-3229
Hauptverfasser:	Suring, Wouter, Meusemann, Karen, Blanke, Alexander, Mariën, Janine, Schol, Tim, Agamennone, Valeria, Faddeeva‐Vakhrusheva, Anna, Berg, Matty P., Brouwer, Abraham, Straalen, Nico M., Roelofs, Dick
Format:	Artikel
Sprache:	eng
Schlagworte:	ABC transporter Amides Animals antibiotic biosynthesis Aquatic insects Arthropod Proteins - genetics Arthropods - enzymology Arthropods - genetics Assaying Bacteria beta-Lactams Biological evolution Biosynthesis Cephamycins Collembola Correlation Ecology Enzyme-linked immunosorbent assay Evolution Folsomia candida Fungi Gene clusters gene expression Gene transfer Genes Genomes Heat shock horizontal gene transfer Isopenicillin N synthase Multigene Family Oxidoreductases - genetics Penicillin Peptide Synthases - genetics Phylogeny Soils Valine β-Lactam antibiotics
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